This blog reports new ideas and work on mind, brain, behavior, psychology, and politics - as well as random curious stuff. (Try the Dynamic Views at top of right column.)
Wednesday, June 04, 2008
Update on resveratrol and aging...
Check out Nicholas Wade's article in today's NY Times. It includes mention of the report in a PLoS ONE article by Prolla and Weindruch's group here at Wisconsin that both caloric restriction and low amounts of resveratrol (near the amount of resveratrol and resveratrol-like compounds found in a 5 ounce glass of red wine) are sufficient to inhibit gene expression profiles associated with cardiac and skeletal muscle aging, and prevent age-related cardiac dysfunction. Dietary resveratrol also mimics the effects of caloric restriction in insulin mediated glucose uptake in muscle.
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