As a followup to the previous post on The Neurobiology of Stress I want to point to Maggie Jackson's opinion piece in the NYTimes titled "How to Thrive in an Uncertain World." A few clips:
...a wave of new scientific discoveries reveals that learning to lean into uncertainty in times of rapid change is a promising antidote to mental distress, not a royal road to angst, as many of us assume...Studies of the pandemic era offer a starting illustration of the links between uncertainty and flourishing. Ohio State researchers have found that adults who scored high on a measure of “intolerance of uncertainty” were more likely to struggle with stress and anxiety during the pandemic....a British study found. In contrast, those who struggle less with uncertainty were more likely to accept the realities of the situation.
Tolerating and even delighting in uncertainty doesn’t merely help us to accept life’s unpredictability; it also readies us to learn and adapt. Each day, the brain uses honed mental models about how the world works, which are used to process a shifting environment. When we meet something unexpected, a neural “prediction error” signals a mismatch between what we assumed would occur and what our senses tell us. Yet our uneasy sense of not knowing triggers a host of beneficial neural changes, including heightened attention, bolstered working memory and sensitivity to new information. The brain is preparing to update our knowledge of the world. Uncertainty offers the opportunity for life to go in different directions...and that is exciting..
The article continues to describe several experiments showing that generalized anxiety disorder can be relieved by therapy sessions that focus on reducing aversion to uncertainty by introducing it in small doses.