Wednesday, December 14, 2016

Why does time fly when you’re having fun? Dopamine neurons…

Soares et al. find by observing timing behavior in mice that dopaminergic neurons control temporal judgments on a time scale of seconds.
Our sense of time is far from constant. For instance, time flies when we are having fun, and it slows to a trickle when we are bored. Midbrain dopamine neurons have been implicated in variable time estimation. However, a direct link between signals carried by dopamine neurons and temporal judgments is lacking. We measured and manipulated the activity of dopamine neurons as mice judged the duration of time intervals. We found that pharmacogenetic suppression of dopamine neurons decreased behavioral sensitivity to time and that dopamine neurons encoded information about trial-to-trial variability in time estimates. Last, we found that transient activation or inhibition of dopamine neurons was sufficient to slow down or speed up time estimation, respectively. Dopamine neuron activity thus reflects and can directly control the judgment of time.

1 comment:

  1. Boredom is a state of mind, as we all know. Some times we don't feel like doing anything but it always good to use the time in some productive ways during creative things.