Friday, April 01, 2016

Are we all sexists and racists?

I want to point to Miller's review of work of Levanon et al., as well as other studies, showing that that when women have moved into occupations in large numbers, those jobs have begun paying less even after controlling for education, work experience, skills, race and geography.
A striking example is to be found in the field of recreation — working in parks or leading camps — which went from predominantly male to female from 1950 to 2000. Median hourly wages in this field declined 57 percentage points, accounting for the change in the value of the dollar, according to a complex formula used by Professor Levanon. The job of ticket agent also went from mainly male to female during this period, and wages dropped 43 percentage points...The same thing happened when women in large numbers became designers (wages fell 34 percentage points), housekeepers (wages fell 21 percentage points) and biologists (wages fell 18 percentage points). The reverse was true when a job attracted more men. Computer programming, for instance, used to be a relatively menial role done by women. But when male programmers began to outnumber female ones, the job began paying more and gained prestige.
In the vein of work described in a previous MindBlog post, an excellent article by Ojiaku, a former Neuroscience Graduate Student at the University of Wisconsin, gives extensive references to work demonstrating that our unconscious racism starts early, and creates a deadly empathy gap. The studies Ojiaku cites:
...showed racially biased differences in cognitive and emotion-related brain regions, including the anterior cingulate cortex (ACC). One of the ACC’s functions is registering when you experience your own pain or empathy for another person’s pain. In the study, Chinese and Caucasian college students were shown video clips of both Chinese and Caucasian faces either in pain or not in pain as scientists conducted brain scans. The researchers measured increased ACC activity in the brains of those viewing painful expressions on the faces belonging to their own race, but decreased ACC activity when viewing pain in another race, uncovering a racially biased difference in empathetic response to pain in the brain.
Another study:
...asked participants to view video images of white, black, and violet-illuminated (for racially neutral) hands being pricked with a needle. While watching the prick, the volunteers were tested for their empathetic response via transcranial magnetic stimulation (TMS); the greater the reaction to the stimulation, the higher the empathetic response to the pain...Interestingly enough, both black and white participants had an adequately empathetic response to seeing the violet hand being pricked. However, all of the participants – both black and white – failed to react as strongly to the pain of someone who was outside their racial group. The study also found that people who scored higher in racial bias on the IAT (implicit association test) – meaning that they showed more implicit preferences for faces belonging to their own race – also showed less reactivity to pain experienced by someone from another race.
The last straw:
...is a study from the University of Iowa published in Psychological Science in February 2016. Incredibly, the researchers found that when white test subjects were primed with photos of five-year-old black boys, they were far more likely to mistake objects such as toys for guns – or even to claim to see guns when there were none. In sharp contrast, when subjects were primed with photos of five-year-old white boys before seeing the objects, the effect reserved, as they were more likely to mistake guns for toys. These findings are ominous for black children, because it shows that youth does not mitigate their potential to become targets of racist events, as in the case of the 12-year-old Tamir Rice, a young black boy carrying a toy ‘BB gun’ in a park in Cleveland, Ohio, whom the police shot in less than two seconds after arriving on the scene.

Thursday, March 31, 2016

Another social science, Economics, looks at itself.

Mindblog recently noted a large study that tested the replicability of studies in psychology journals. Only 36% of the findings were repeated. The quality of results has also been questioned in many fields such as medicine, neuroscience, and genetics. Camerer et al. have now tested the replicability of experiments published in top-tier economics journals, finding that two-thirds of the 18 studies examined yielded replicable estimates of effect size and direction. Their abstract:
The replicability of some scientific findings has recently been called into question. To contribute data about replicability in economics, we replicated 18 studies published in the American Economic Review and the Quarterly Journal of Economics between 2011 and 2014. All of these replications followed predefined analysis plans that were made publicly available beforehand, and they all have a statistical power of at least 90% to detect the original effect size at the 5% significance level. We found a significant effect in the same direction as in the original study for 11 replications (61%); on average, the replicated effect size is 66% of the original. The replicability rate varies between 67% and 78% for four additional replicability indicators, including a prediction market measure of peer beliefs.

Wednesday, March 30, 2016

Overkill in techno-aids for 'Mens Sana in Corpore Sano'

None of us would argue with the 'sound mind in a sound body' injunction from Juvenal’s Latin satires (~100 AD), a goal that can be accomplished by diligent pursuit of a few simple activities. Two NYTimes articles note how modern technology manages, for a profit, to vastly encumber that pursuit.

With regard to 'sound mind,' Gelles notes:
The other morning, I woke up and brewed a cup of Mindful Lotus tea ($6 for 20 bags). On the subway, I loaded the Headspace app on my iPhone and followed a guided mindfulness exercise ($13 a month for premium content). Later in the day, I dropped by Mndfl, a meditation studio in Greenwich Village ($20 for a 30-minute class)...There are more than two dozen mindfulness apps for smartphones, some offering $400 lifetime subscriptions. The Great Courses has two mindfulness packages, each with a couple of dozen DVDs for $250. For an enterprising contemplative, it’s never been easier to make a buck...On a recent trip to Whole Foods, near the kombucha, I came across a new product from the health food maker Earth Balance: a dairy-free mayonnaise substitute called Mindful Mayo ($4.50 a jar). Then, in line, I picked up a copy of Mindful magazine ($6)....With so many mindful goods and services for sale, it can be easy to forget that mindfulness is a quality of being, not a piece of merchandise
...with so many cashing in on the meditation craze, it’s hard not to wonder whether something essential is being lost...Increasingly, mindfulness is being packaged as a one-minute reprieve, an interlude between checking Instagram and starting the next episode of “House of Cards.” One company proclaims it has found the “minimum effective dose” of meditation that will change your life. On Amazon, you can pick up “One-Minute Mindfulness: 50 Simple Ways to Find Peace, Clarity, and New Possibilities in a Stressed-Out World.” Dubious courses promise to help people “master mindfulness” in a few weeks.
More often than not, however, the people I know who take time to meditate — carefully observing thoughts, emotions and sensations — are sincere in their aspirations to become less stressed, more accepting and at least a little happier.
Hutchinson discusses the greater than billion dollar market for body fitness aids (which are not used by more than half their buyers six months after their purchase) suggesting:
...a more fundamental question about our rapid adoption of wearable fitness tech: Is the data we collect with these devices actually useful?...Last September, in The British Journal of Sports Medicine, Australian researchers published a review of studies that compared subjective and objective measures of “athlete well-being” during training. The objective measures included state-of-the-art monitoring of heart rate, blood, hormones and more; the subjective measure boiled down to asking the athletes how they felt. The results were striking: The researchers found that as the athletes worked out, their own perception registered changes in training stress with “superior sensitivity and consistency” to the high tech measures...running with a GPS watch “slackens the bond between perception and action.” In other words, when you’re running, instead of speeding up or slowing down based on immediate and intuitive feedback from your body and environment, you’re inserting an unwieldy extra cognitive step that relies on checking your device as you go.
On the positive side:
Health researchers also want to use your tracked data to figure out what works in the real world to improve health and fitness, rather than testing theories in the artificial conditions of the lab. An analysis of in-the-wild data from 4.2 million MyFitnessPal users, for example, recently yielded unexpected insights into the habits of successful weight-losers compared with unsuccessful ones: They ate nearly a third more fiber, and 11 percent less meat. And the dietary changes the successful dieters made between 2014 and 2015 bucked broader trends: They consumed more grains, cereal and raw fruit, but fewer eggs.
As prosaic as it sounds, this is the greatest promise of the wearables revolution. Once the novelty of tracking your exercise habits wears off, knowing how many steps you took today or what your resting heart rate was yesterday soon loses its interest. But together, 100 million of us wearing wristbands could uncover some truly valuable insights into what works to make us healthier and fitter.
Perhaps the most effective and simple way to increase aerobic fitness: use a jump rope!

Tuesday, March 29, 2016

Storing long term emotional memories.

A Journal of Neuroscience precis of an article by Cambiaghi et al., slightly edited:
When we remember events, we often also remember what we were feeling at the time. Cambiaghi et al. asked where in the brain we store such connections. To answer this, they conditioned rats to associate a tone with an unpleasant experience. They then simultaneously recorded from two brain regions, the higher-order auditory cortex and the amygdala, 1 day and 1 month after the conditioning. Animals displayed fearful behavior at both time points, and both areas showed learning-evoked changes. However, the two brain regions only interacted significantly after 1 month had passed (The cue increased the synchrony of their firing.) The degree of interaction predicted the animals' ability to recognize the tone as unpleasant.

Monday, March 28, 2016

Screenagers - brain executive function immediately diminished by television

An article by Jolly points to interesting work by Lillard and Peterson. Their summary:
The goal of this research was to study whether a fast-paced television show immediately influences preschool-aged children's executive function (eg, self-regulation, working memory).  Sixty 4-year-olds were randomly assigned to watch a fast-paced television cartoon or an educational cartoon or draw for 9 minutes. They were then given 4 tasks tapping executive function, including the classic delay-of-gratification and Tower of Hanoi tasks. Parents completed surveys regarding television viewing and child's attention. Children who watched the fast-paced television cartoon performed significantly worse on the executive function tasks than children in the other 2 groups when controlling for child attention, age, and television exposure.  Just 9 minutes of viewing a fast-paced television cartoon had immediate negative effects on 4-year-olds' executive function. Parents should be aware that fast-paced television shows could at least temporarily impair young children's executive function.

Friday, March 25, 2016

Our progression towards a nation of rich and poor

A fascinating and foreboding piece by Rank and Hirschl describe their development of a "economic risk calculator' available at riskcalculator.org
The idea behind our approach is similar to the idea behind a doctor’s ability to predict your risk of heart disease. Using several pieces of information (blood pressure, cholesterol, etc.), your doctor can make a reasonable estimate of your chances of having a heart attack in the next 10 years. These numbers are based on statistical patterns derived from a very large sample of families that make up the Framingham Heart Study, the longitudinal study of cardiovascular health that began in 1948.
Our predictions of economic risk work in a similar way. Using hundreds of thousands of case records taken from a longitudinal study of Americans that began in 1968, we estimate the likelihood — based on factors like race, education, marital status and age — of an individual’s falling below the official poverty line during the next five, 10 or 15 years. (The poverty line for a family of four in 2015 was approximately $24,000.)
Take someone ... who is in his or her later 30s, white, not married, with an education beyond high school. It turns out that the 15-year risk of poverty for such a person is actually 32 percent. In other words, one-third of such individuals will experience at least one year below the poverty line in the not-so-distant future...between the ages of 20 and 75, nearly 60 percent of Americans will spend at least one year below the official poverty line, and three-quarters will experience a year below 150 percent of the poverty line.
We are in danger of becoming an economically polarized society in which a small percentage of the population is free from economic risk, while a vast majority of Americans will encounter poverty as a normal part of life.

Thursday, March 24, 2016

Suppressing memory of trauma causes forgetting of other memories.

An interesting article from Hulbert et.al. on how suppressing memory of a trauma also causes forgetting of unrelated experiences in the period surrounding the trauma.:
Hippocampal damage profoundly disrupts the ability to store new memories of life events. Amnesic windows might also occur in healthy people due to disturbed hippocampal function arising during mental processes that systemically reduce hippocampal activity. Intentionally suppressing memory retrieval (retrieval stopping) reduces hippocampal activity via control mechanisms mediated by the lateral prefrontal cortex. Here we show that when people suppress retrieval given a reminder of an unwanted memory, they are considerably more likely to forget unrelated experiences from periods surrounding suppression. This amnesic shadow follows a dose-response function, becomes more pronounced after practice suppressing retrieval, exhibits characteristics indicating disturbed hippocampal function, and is predicted by reduced hippocampal activity. These findings indicate that stopping retrieval engages a suppression mechanism that broadly compromises hippocampal processes and that hippocampal stabilization processes can be interrupted strategically. Cognitively triggered amnesia constitutes an unrecognized forgetting process that may account for otherwise unexplained memory lapses following trauma.

Wednesday, March 23, 2016

Vasopressin increases human risky cooperative behavior

From Brunnlieb et al.:

Significance
Most forms of cooperative behavior take place in a mutually beneficial context where cooperation is risky as its success depends on unknown actions of others. In two pharmacological experiments, we show that intranasal administration of arginine vasopressin (AVP), a hormone that regulates mammalian social behaviors such as monogamy and aggression, increases humans’ tendency to engage in mutually beneficial cooperation. Several control tasks ruled out that AVP’s effects were driven by increased willingness to bare risks in the absence of social context, beliefs about the actions of one’s partner, or altruistic concerns. Our findings provide novel causal evidence for a biological factor underlying cooperation and are in accord with previous findings that cooperation is intrinsically rewarding for humans.
Abstract
The history of humankind is an epic of cooperation, which is ubiquitous across societies and increasing in scale. Much human cooperation occurs where it is risky to cooperate for mutual benefit because successful cooperation depends on a sufficient level of cooperation by others. Here we show that arginine vasopressin (AVP), a neuropeptide that mediates complex mammalian social behaviors such as pair bonding, social recognition and aggression causally increases humans’ willingness to engage in risky, mutually beneficial cooperation. In two double-blind experiments, male participants received either AVP or placebo intranasally and made decisions with financial consequences in the “Stag hunt” cooperation game. AVP increases humans’ willingness to cooperate. That increase is not due to an increase in the general willingness to bear risks or to altruistically help others. Using functional brain imaging, we show that, when subjects make the risky Stag choice, AVP down-regulates the BOLD signal in the left dorsolateral prefrontal cortex (dlPFC), a risk-integration region, and increases the left dlPFC functional connectivity with the ventral pallidum, an AVP receptor-rich region previously associated with AVP-mediated social reward processing in mammals. These findings show a previously unidentified causal role for AVP in social approach behavior in humans, as established by animal research.

Tuesday, March 22, 2016

Pictures of green spaces make you happier.

Reynolds points to work by van den Berg et al. showing that viewing pictures of green versus built urban areas enhances parasympathetic nervous system activity that is calming and restorative. This results are consonant with those obtained by a Stanford study on the effects of a brief nature experience on rumination, and also with discussions of "blue mind" (cf. calming effect of blue water) versus "red mind."
This laboratory study explored buffering and recovery effects of viewing urban green and built spaces on autonomic nervous system activity. Forty-six students viewed photos of green and built spaces immediately following, and preceding acute stress induction. Simultaneously recorded electrocardiogram and impedance cardiogram signal was used to derive respiratory sinus arrhythmia (RSA) and pre-ejection period (PEP), indicators of respectively parasympathetic and sympathetic activity. The findings provide support for greater recovery after viewing green scenes, as marked by a stronger increase in RSA as a marker of parasympathetic activity. There were no indications for greater recovery after viewing green scenes in PEP as a marker of sympathetic activity, and there were also no indications of greater buffering effects of green space in neither RSA nor PEP. Overall, our findings are consistent with a predominant role of the parasympathetic nervous system in restorative effects of viewing green space.

Monday, March 21, 2016

Rachmaninoff Morceaux de fantasie Op. 3, No. 4, Polichinelle

This is the last of the pieces from my recent recitals that I want to pass on to readers - a robust beginning for a Monday morning!


Anxiety suppresses prefrontal cortex decision ability.

Interesting work from Park et al.:
A debilitating aspect of anxiety is its impact on decision making and flexible control of behavior. These cognitive constructs depend on proper functioning of the prefrontal cortex (PFC). Understanding how anxiety affects PFC encoding of cognitive events is of great clinical and evolutionary significance. Using a clinically valid experimental model, we find that, under anxiety, decision making may be skewed by salient and conflicting environmental stimuli at the expense of flexible top-down guided choices. We also find that anxiety suppresses spontaneous activity of PFC neurons, and weakens encoding of task rules by dorsomedial PFC neurons. These data provide a neuronal encoding scheme for how anxiety disengages PFC during decision making.

Friday, March 18, 2016

Impatience, aging, and leukocyte telomere length.

Yim et al. note in young college volunteers a correlation between a chemical marker of biological aging (leukocyte telomere length, abbr. LTL) and impatience (delay discounting). The wording of the abstract flirts with conflating correlations with causes, and directions of implied causes is not clear - does impatience causes cellular aging or does cellular aging cause impatience?  People with shorter telomeres might be more impatient because they are not going to be around as long?   (Or, do we have  a correlation as spurious as that noted between mortgage loan rates and sunspot frequency in the 1950's? Let the reader decide... ).

Significance
This paper makes a singular contribution to understanding the association between biological aging indexed by leukocyte telomeres length (LTL) and delay discounting measured in an incentivized behavioral economic task. In a large group of young, healthy undergraduates, steeper delay discounting is significantly associated with shorter LTL, while controlling for risk attitude and health-related behaviors. Notably, we found that delay discounting and risk attitude—two fundamental determinants of economic preferences—are independently associated with LTL. Moreover, for the first time to our knowledge, the effects of well-studied oxytocin and estrogen receptor polymorphisms are shown to specifically moderate the impact of impatience on LTL. Our work suggests a path to integrate behavioral economic methodology to supposed biological mechanisms associated with health outcomes. 
Abstract 
In a graying world, there is an increasing interest in correlates of aging, especially those found in early life. Leukocyte telomere length (LTL) is an emerging marker of aging at the cellular level, but little is known regarding its link with poor decision making that often entails being overly impatient. Here we investigate the relationship between LTL and the degree of impatience, which is measured in the laboratory using an incentivized delay discounting task. In a sample of 1,158 Han Chinese undergraduates, we observe that steeper delay discounting, indexing higher degree of impatience, is negatively associated with LTL. The relationship is robust after controlling for health-related variables, as well as risk attitude—another important determinant of decision making. LTL in females is more sensitive to impatience than in males. We then asked if genes possibly modulate the effect of impatient behavior on LTL. The oxytocin receptor gene (OXTR) polymorphism rs53576, which has figured prominently in investigations of social cognition and psychological resources, and the estrogen receptor β gene (ESR2) polymorphism rs2978381, one of two gonadal sex hormone genes, significantly mitigate the negative effect of impatience on cellular aging in females. The current results contribute to understanding the relationship between preferences in decision making, particularly impatience, and cellular aging, for the first time to our knowledge. Notably, oxytocin and estrogen receptor polymorphisms temper accelerated cellular aging in young females who tend to make impatient choices.

Thursday, March 17, 2016

Political Substance Abuse: Donald Trump in Florida

I have to pass this on.

Seasonality in human cognitive brain responses

A brief review in PNAS points to an article by Meyer et.al.:
Mood changes have been linked to seasonality, but little is known about how other human brain functions may vary according to the seasons. Christelle Meyer et al. measured the cognitive brain function of 28 volunteers at different times of the year. For each testing period, each participant spent 5 days in the laboratory, devoid of seasonal cues, such as daylight, and without access to the external world. At the end of the 5-day period, the authors used functional MRI to assess sustained attention and higher executive function in two separate tasks. Performance on both tasks remained constant, but the brain resources used to complete each task changed with the seasons. Brain activity related to sustained attention peaked in June near the summer solstice and was lowest near the winter solstice. In contrast, working memory-related brain activity, a higher-order task, peaked in fall and was lower near the spring equinox. The authors report that these results did not correlate with endocrine measures, such as melatonin, or neurophysiological measures of alertness and sleep. According to the authors, in addition to daily circadian rhythms, certain brain functions may be more seasonal than previously appreciated and that seasonal rhythmicity may be specific to the cognitive process.
Seasonal variations in brain responses to two cognitive tasks, where the black lines represent the mean values.

Wednesday, March 16, 2016

Rachmaninoff Morceaux de fantasie Op. 3 No. 1 Elegie

I continue to pass on a few of the pieces done at my recent piano recitals.

 

Tuesday, March 15, 2016

Our brains remember the good stuff.

Anderson et al. show how our brains are attracted to items that have pleased us in the past, even if they are no longer relevant. People in a study were asked to look at a computer screen filled with colored objects and find the red and green ones, They received a small amount of money for each red or green object found. On the next day, the subjects were asked to find certain shapes on the screen, the color being irrelevant. Even so, when a red object appeared it captured attention, and PET brain imaging showed dopamine release in the ventral striatum, which plays a role in reward learning. Here is their technical abstract:

Highlights
•We examined the neural correlates of value-based attention using PET
•Previously reward-associated stimuli involuntary captured attention as distractors
•Such attentional capture was predicted by dopamine release in the dorsal striatum
•Our findings elucidate the neurochemical basis of value-based distraction

Summary
Reward learning gives rise to strong attentional biases. Stimuli previously associated with reward automatically capture visual attention regardless of intention. Dopamine signaling within the ventral striatum plays an important role in reward learning, representing the expected reward initiated by a cue. How dopamine and the striatum may be involved in maintaining behaviors that have been shaped by reward learning, even after reward expectancies have changed, is less well understood. Nonspecific measures of brain activity have implicated the striatum in value-based attention. However, the neurochemical mechanisms underlying the attentional priority of learned reward cues remain unexplored. Here, we investigated the contribution of dopamine to value-based attention using positron emission tomography (PET) with [11C]raclopride. We show that, in the explicit absence of reward, the magnitude of attentional capture by previously reward-associated but currently task-irrelevant distractors is correlated across individuals with changes in available D2/D3 dopamine receptors (presumably due to intrasynaptic dopamine) linked to distractor processing within the right caudate and posterior putamen. Our findings provide direct evidence linking dopamine signaling within the striatum to the involuntary orienting of attention, and specifically to the attention-grabbing quality of learned reward cues. These findings also shed light on the neurochemical basis of individual susceptibility to value-driven attentional capture, which is known to play a role in addiction. More broadly, the present study highlights the value and feasibility of using PET to relate changes in the release of a neurotransmitter to learning-dependent changes in healthy adults.

Monday, March 14, 2016

Brain games and driving safely.

I've done a number of posts on brain games (cf. here, here, and here) and their critics. When I overcome my lassitude and occasionally return to dink with one of the BrainHQ games, I am struck by at least temporary improvements in the cognitive activity being refined, particularly with the vision exercises dealing with useful field of view, contrast sensitivity, etc. The exercise called Double Decision seems to me especially effective. I notice an effect on my driving after playing it. I thought I would pass on this BrainHQ web page on research on BrainHQ exercises. Their claim is that the studies have shown that after training, drivers on average:

-Make 38% fewer dangerous driving maneuvers
-Can stop 22 feet sooner when driving 55 miles per hour
-Feel more confident driving in difficult conditions (such as at night, in bad weather, or in new places)
-Cut their at-fault crash risk by 48%
-Keep their license later in life

Wearing a bike helmet increases risk taking.

From Gamble and Walker:
Humans adapt their risk-taking behavior on the basis of perceptions of safety; this risk-compensation phenomenon is typified by people taking increased risks when using protective equipment. Existing studies have looked at people who know they are using safety equipment and have specifically focused on changes in behaviors for which that equipment might reduce risk. Here, we demonstrated that risk taking increases in people who are not explicitly aware they are wearing protective equipment; furthermore, this happens for behaviors that could not be made safer by that equipment. In a controlled study in which a helmet, compared with a baseball cap, was used as the head mount for an eye tracker, participants scored significantly higher on laboratory measures of both risk taking and sensation seeking. This happened despite there being no risk for the helmet to ameliorate and despite it being introduced purely as an eye tracker. The results suggest that unconscious activation of safety-related concepts primes globally increased risk propensity.

Friday, March 11, 2016

Brahms Waltzes Op. 39, Nos. 1,13,14

Recorded on my Steinway B, now in my Fort Lauderdale condo. I did this piece in recitals in Madison WI and Fort Lauderdale in the past 6 months, and now have made a good quality video recording for my youtube channel. I plan to do this with several of the pieces played at the recitals.


The first of the waltzes has a very robust opening that always brings back memories of my listening to a Saturday morning radio program produced by KTBC in Austin Texas, that invited students taking music lessons to perform a piece, which I dutifully did when I was 12. The program’s opening music was the first of these Brahms waltzes, and I couldn’t imagine ever being able to play something that sounded so difficult.

Thursday, March 10, 2016

Stephen Wolfram on A.I. and the future of civilization

Some clips from a Wolfram discussion (well worth reading) that notes the limits of doing things with machines...
The machine is able to execute things, but something or someone has to define what its goals should be and what it's trying to execute.
What makes us different from all these things? What makes us different is the particulars of our history, which gives us our notions of purpose and goals. That's a long way of saying when we have the box on the desk that thinks as well as any brain does, the thing it doesn't have, intrinsically, is the goals and purposes that we have. Those are defined by our particulars—our particular biology, our particular psychology, our particular cultural history.
The thing we have to think about as we think about the future of these things is the goals. That's what humans contribute, that's what our civilization contributes—execution of those goals; that's what we can increasingly automate. We've been automating it for thousands of years. We will succeed in having very good automation of those goals. I've spent some significant part of my life building technology to essentially go from a human concept of a goal to something that gets done in the world.