This blog reports new ideas and work on mind, brain, behavior, psychology, and politics - as well as random curious stuff. (Try the Dynamic Views at top of right column.)
Monday, November 07, 2022
Sadder but Wiser? Maybe Not.
Friday, November 04, 2022
Senescent cells targeted by anti-aging therapies may not be all bad
Wednesday, November 02, 2022
Well being increases with diversity of social connections.
From Collins et al.:
Significance
The link between social connection and well-being is well-documented: Happier people tend to spend more time with others, and people experience greater happiness while socially engaged. But, over and above people’s total amount of social interaction, which set of interactions—with which types of relationship partners (e.g., family members, close friends, acquaintances, strangers), and how many interactions with each type—is most predictive of well-being? Building on research showing the benefits of variety—in activities, experiences, and emotions—for well-being, we document a link between the relational diversity of people’s social portfolios and well-being. Assessing the social interactions and happiness of over 50,000 people reveals that interacting with a more diverse set of relationship types predicts higher well-being.Abstract
We document a link between the relational diversity of one’s social portfolio—the richness and evenness of relationship types across one’s social interactions—and well-being. Across four distinct samples, respondents from the United States who completed a preregistered survey (n = 578), respondents to the American Time Use Survey (n = 19,197), respondents to the World Health Organization’s Study on Global Aging and Adult Health (n = 10,447), and users of a French mobile application (n = 21,644), specification curve analyses show that the positive relationship between social portfolio diversity and well-being is robust across different metrics of well-being, different categorizations of relationship types, and the inclusion of a wide range of covariates. Over and above people’s total amount of social interaction and the diversity of activities they engage in, the relational diversity of their social portfolio is a unique predictor of well-being, both between individuals and within individuals over time.
Monday, October 31, 2022
Molecular markers of eventual chronic diseases of aging are higher in young adults of lower socioeconomic status.
Sobering work from Shanahan et al.:
Significance
The analysis of gene expression in peripheral whole blood of US young adults in their late 30s revealed socioeconomic status-based inequalities in the molecular underpinnings of the most common chronic conditions of aging. Associations involved immune, inflammatory, ribosomal, and metabolic pathways, and extra- and intra-cellular signaling. Body mass index was a plausible, sizable mediator of many associations. Results point to new ways of thinking about how social inequalities “get under the skin” and also call for renewed efforts to prevent chronic conditions of aging decades before diagnoses.Abstract
Many common chronic diseases of aging are negatively associated with socioeconomic status (SES). This study examines whether inequalities can already be observed in the molecular underpinnings of such diseases in the 30s, before many of them become prevalent. Data come from the National Longitudinal Study of Adolescent to Adult Health (Add Health), a large, nationally representative sample of US subjects who were followed for over two decades beginning in adolescence. We now have transcriptomic data (mRNA-seq) from a random subset of 4,543 of these young adults. SES in the household-of-origin and in young adulthood were examined as covariates of a priori-defined mRNA-based disease signatures and of specific gene transcripts identified de novo. An SES composite from young adulthood predicted many disease signatures, as did income and subjective status. Analyses highlighted SES-based inequalities in immune, inflammatory, ribosomal, and metabolic pathways, several of which play central roles in senescence. Many genes are also involved in transcription, translation, and diverse signaling mechanisms. Average causal-mediated effect models suggest that body mass index plays a key role in accounting for these relationships. Overall, the results reveal inequalities in molecular risk factors for chronic diseases often decades before diagnoses and suggest future directions for social signal transduction models that trace how social circumstances regulate the human genome.
Friday, October 28, 2022
Observing the activity of our prosocial brains
Interesting work from Lockwood et al., open source with nice graphics:
Highlights
• Prosocial behaviors frequently involve exerting effort
• Human participants completed an effort-based decision-making task during fMRI
• The anterior cingulate gyrus represented the effort costs of prosocial acts
• Ventral tegmental area and ventral insula represented value for oneselfSummary
Prosocial behaviors—actions that benefit others—are central to individual and societal well-being. Although the mechanisms underlying the financial and moral costs of prosocial behaviors are increasingly understood, this work has often ignored a key influence on behavior: effort. Many prosocial acts are effortful, and people are averse to the costs of exerting them. However, how the brain encodes effort costs when actions benefit others is unknown. During fMRI, participants completed a decision-making task where they chose in each trial whether to “work” and exert force (30%–70% of maximum grip strength) or “rest” (no effort) for rewards (2–10 credits). Crucially, on separate trials, they made these decisions either to benefit another person or themselves. We used a combination of multivariate representational similarity analysis and model-based univariate analysis to reveal how the costs of prosocial and self-benefiting efforts are processed. Strikingly, we identified a unique neural signature of effort in the anterior cingulate gyrus (ACCg) for prosocial acts, both when choosing to help others and when exerting force to benefit them. This pattern was absent for self-benefiting behaviors. Moreover, stronger, specific representations of prosocial effort in the ACCg were linked to higher levels of empathy and higher subsequent exerted force to benefit others. In contrast, the ventral tegmental area and ventral insula represented value preferentially when choosing for oneself and not for prosocial acts. These findings advance our understanding of the neural mechanisms of prosocial behavior, highlighting the critical role that effort has in the brain circuits that guide helping others.
Wednesday, October 26, 2022
A lucid exposition on non-dual awareness by James Low
If you want stability, if you want real peace, you already have that in the nature of awareness. But if you look to manifestation, to patterning of yourself, to thinking you could establish a stable personalty, to live a life in which you were happy all the time, or in which you were your own person, that way madness lies. To find our original face, to find the ground of our primordial being, we need to release our fixation on the dialogic movement of subject and object, and allow ourselves to be the space within which the movement of experience is occurring. Awareness means being aware that we are present without being something as such. This is a great mystery. When we look at phenomena the world, things exist as something. A car is not a cow, an apple is not an orange, compare and contrast, category allocation. That’s how our cognition, our conceptual elaboration functions to give a seemingly enduring structure to identifications. But awareness can’t be caught. It’s not a thing. You can’t pin a tail on the donkey, there is no donkey there. The mind is not an object for itself, it is self luminous awareness, but you can’t catch it. You can never know your mind but you can be your mind. We are awareness and that’s a very important distinction.
Monday, October 24, 2022
Generative A.I. - more sociopathic than FaceBook and Twitter?
Have a look at this article on how the sociopathic effects of Facebook and Twitter could be dwarfed by what open source generative A.I. could do. I just played with the DALL-E 2 A.I. system that generates an image when you tell it what you want to see. In response to my request to show "Two abyssinian cats sitting in a window looking out at trees" the following spooky and accurate image appeared.
Saturday, October 22, 2022
New Perspectives on how our Minds Work
I want to pass on to MindBlog readers this link to a lecture I gave this past Friday (10/21/22) to the Univ. of Texas OLLI (Osher Lifelong Learning Institute) UT FORUM group on Oct. 21, 2022. Here is the brief description of the talk:
Abstract
Recent research shows that much of what we thought we knew about how our minds work is wrong. Rather than rising from our essential natures, our emotional and social realities are mainly invented by each of us. Modern and ancient perspectives allow us to have some insight into what we have made.Description
This talk offers a description of how our predictive brains work to generate our perceptions, actions, emotions, concepts, language, and social structures. Our experience that a self or "I" inside our heads is responsible for these behaviors is a useful illusion, but there is in fact no homunculus or discrete place inside our heads where “It all comes together.” Starting before we are born diffuse networks of brain cells begin generating actions and perceiving their consequences to build an internal library of sensing and acting correlations that keep us alive and well, a library that is the source of predictions about what we might expect to happen next in our worlds. Insights from both modern neuroscience research and ancient meditative traditions allow us to partially access and sometimes change this archive that manages our behaviors.
Friday, October 21, 2022
Anxiety - What is it, when is it useful, when is it not?
Martin Seligman and learned helplessness versus helpfulness
Eustress - beneficial stress
Bruce McEwen on good and bad stress
Robert Sapolsky on chronic stress
A deeper look into what our bodies are doing during arousal and calm (click on the arrows at bottom left of presentation frame to expand to full screen)
Wednesday, October 19, 2022
Facebook has no idea where it keeps our personal data.
...has amassed so much data on so many billions of people and organized it so confusingly that full transparency is impossible on a technical level. In the March 2022 hearing, Zarashaw and Steven Elia, a software engineering manager, described Facebook as a data-processing apparatus so complex that it defies understanding from within. The hearing amounted to two high-ranking engineers at one of the most powerful and resource-flush engineering outfits in history describing their product as an unknowable machine.
The special master at times seemed in disbelief, as when he questioned the engineers over whether any documentation existed for a particular Facebook subsystem. “Someone must have a diagram that says this is where this data is stored,” he said, according to the transcript. Zarashaw responded: “We have a somewhat strange engineering culture compared to most where we don’t generate a lot of artifacts during the engineering process. Effectively the code is its own design document often.” He quickly added, “For what it’s worth, this is terrifying to me when I first joined as well.”
The fundamental problem, according to the engineers in the hearing, is that Facebook’s sprawl has made it impossible to know what it consists of anymore; the company never bothered to cultivate institutional knowledge of how each of these component systems works, what they do, or who’s using them. There is no documentation of what happens to your data once it’s uploaded, because that’s just never been something the company does, the two explained. “It is rare for there to exist artifacts and diagrams on how those systems are then used and what data actually flows through them,”
Monday, October 17, 2022
Musical rhythm training improves short-term memory for faces
From Zanto et al:
Significance
Musical training can improve numerous cognitive functions associated with musical performance. Yet, there is limited evidence that musical training may benefit nonmusical tasks and it is unclear how the brain may enable such a transfer of benefit. To address this, nonmusicians were randomized to receive 8 wk of either musical rhythm training or word search training. Memory for faces was assessed pre- and post-training while electroencephalography data were recorded to assess changes in brain activity. Results showed that only musical rhythm training improved face memory, which was associated with increased activity in the superior parietal region of the brain when encoding and maintaining faces. Thus, musical rhythm training can improve face memory by facilitating how the brain encodes and maintains memories.Abstract
Playing a musical instrument engages numerous cognitive abilities, including sensory perception, selective attention, and short-term memory. Mounting evidence indicates that engaging these cognitive functions during musical training will improve performance of these same functions. Yet, it remains unclear the extent these benefits may extend to nonmusical tasks, and what neural mechanisms may enable such transfer. Here, we conducted a preregistered randomized clinical trial where nonmusicians underwent 8 wk of either digital musical rhythm training or word search as control. Only musical rhythm training placed demands on short-term memory, as well as demands on visual perception and selective attention, which are known to facilitate short-term memory. As hypothesized, only the rhythm training group exhibited improved short-term memory on a face recognition task, thereby providing important evidence that musical rhythm training can benefit performance on a nonmusical task. Analysis of electroencephalography data showed that neural activity associated with sensory processing and selective attention were unchanged by training. Rather, rhythm training facilitated neural activity associated with short-term memory encoding, as indexed by an increased P3 of the event-related potential to face stimuli. Moreover, short-term memory maintenance was enhanced, as evidenced by increased two-class (face/scene) decoding accuracy. Activity from both the encoding and maintenance periods each highlight the right superior parietal lobule (SPL) as a source for training-related changes. Together, these results suggest musical rhythm training may improve memory for faces by facilitating activity within the SPL to promote how memories are encoded and maintained, which can be used in a domain-general manner to enhance performance on a nonmusical task.
Friday, October 14, 2022
Sleepless and unhelpful
Humans help each other. This fundamental feature of homo sapiens has been one of the most powerful forces sculpting the advent of modern civilizations. But what determines whether humans choose to help one another? Across 3 replicating studies, here, we demonstrate that sleep loss represents one previously unrecognized factor dictating whether humans choose to help each other, observed at 3 different scales (within individuals, across individuals, and across societies). First, at an individual level, 1 night of sleep loss triggers the withdrawal of help from one individual to another. Moreover, fMRI findings revealed that the withdrawal of human helping is associated with deactivation of key nodes within the social cognition brain network that facilitates prosociality. Second, at a group level, ecological night-to-night reductions in sleep across several nights predict corresponding next-day reductions in the choice to help others during day-to-day interactions. Third, at a large-scale national level, we demonstrate that 1 h of lost sleep opportunity, inflicted by the transition to Daylight Saving Time, reduces real-world altruistic helping through the act of donation giving, established through the analysis of over 3 million charitable donations. Therefore, inadequate sleep represents a significant influential force determining whether humans choose to help one another, observable across micro- and macroscopic levels of civilized interaction. The implications of this effect may be non-trivial when considering the essentiality of human helping in the maintenance of cooperative, civil society, combined with the reported decline in sufficient sleep in many first-world nations.
Wednesday, October 12, 2022
Third-party punishment by preverbal infants
Third-party punishment of antisocial others is unique to humans and seems to be universal across cultures. However, its emergence in ontogeny remains unknown. We developed a participatory cognitive paradigm using gaze-contingency techniques, in which infants can use their gaze to affect agents displayed on a monitor. In this paradigm, fixation on an agent triggers the event of a stone crushing the agent. Throughout five experiments (total N = 120), we show that eight-month-old infants punished antisocial others. Specifically, infants increased their selective looks at the aggressor after watching aggressive interactions. Additionally, three control experiments excluded alternative interpretations of their selective gaze, suggesting that punishment-related decision-making influenced looking behaviour. These findings indicate that a disposition for third-party punishment of antisocial others emerges in early infancy and emphasize the importance of third-party punishment for human cooperation. This behavioural tendency may be a human trait acquired over the course of evolution.
Monday, October 10, 2022
A sleeping touch improves vision.
Interesting work reported by Onuki et al. in the Journal of Neuroscience:
SIGNIFICANCE STATEMENTTactile sensations can bias our visual perception as a form of cross-modal interaction. However, it was reported only in the awake state. Here we show that repetitive directional tactile motion stimulation on the fingertip during slow wave sleep selectively enhanced subsequent visual motion perception. Moreover, the visual improvement was positively associated with sleep slow wave activity. The tactile motion stimulation during slow wave activity increased the activation at the high beta frequency over the occipital electrodes. The visual improvement occurred in agreement with a hand-centered reference frame. These results suggest that our sleeping brain can interpret tactile information based on a hand-centered reference frame, which can cause the sleep-dependent improvement of visual motion detection.
ABSTRACT
Tactile sensations can bias visual perception in the awake state while visual sensitivity is known to be facilitated by sleep. It remains unknown, however, whether the tactile sensation during sleep can bias the visual improvement after sleep. Here, we performed nap experiments in human participants (n = 56, 18 males, 38 females) to demonstrate that repetitive tactile motion stimulation on the fingertip during slow wave sleep selectively enhanced subsequent visual motion detection. The visual improvement was associated with slow wave activity. The high activation at the high beta frequency was found in the occipital electrodes after the tactile motion stimulation during sleep, indicating a visual-tactile cross-modal interaction during sleep. Furthermore, a second experiment (n = 14, 14 females) to examine whether a hand- or head-centered coordination is dominant for the interpretation of tactile motion direction showed that the biasing effect on visual improvement occurs according to the hand-centered coordination. These results suggest that tactile information can be interpreted during sleep, and can induce the selective improvement of post-sleep visual motion detection.
Friday, October 07, 2022
Liberal Democracy versus Christian Democracy
Could there soon be an American counterpart to Viktor Orban, the Hungarian prime minister, a right-wing populist who in 2018 declared, “We must demonstrate that there is an alternative to liberal democracy: It is called Christian democracy. And we must show that the liberal elite can be replaced with a Christian democratic elite”?
Liberal democracy, Orban continued,
is liberal, while Christian democracy is, by definition, not liberal: it is, if you like, illiberal. And we can specifically say this in connection with a few important issues — say, three great issues. Liberal democracy is in favor of multiculturalism, while Christian democracy gives priority to Christian culture; this is an illiberal concept. Liberal democracy is pro-immigration, while Christian democracy is anti-immigration; this is again a genuinely illiberal concept. And liberal democracy sides with adaptable family models, while Christian democracy rests on the foundations of the Christian family model; once more, this is an illiberal concept.
Or could there soon be an American counterpart to Giorgia Meloni, another right-wing populist and admirer of Orban, now on course to become the next prime minister of Italy?
Meloni’s platform?
I highly recommend reading the rest of Edsall's article on the signals pointing to the vulnerability of the liberal state.Yes to natural families, no to the L.G.B.T. lobby. Yes to sexual identity, no to gender ideology. Yes to the culture of life, no to the abyss of death. No to the violence of Islam, yes to safer borders. No to mass immigration, yes to work for our people.
Wednesday, October 05, 2022
Cognitive and Evolutionary Foundations of Puritanical Morality
Why do many societies moralize apparently harmless pleasures, such as lust, gluttony, alcohol, drugs, and even music and dance? Why do they erect temperance, asceticism, sobriety, modesty, and piety as cardinal moral virtues? According to existing theories, this puritanical morality cannot be reduced to concerns for harm and fairness: it must emerge from cognitive systems that did not evolve for cooperation (e.g., disgust-based "Purity" concerns). Here, we argue that, despite appearances, puritanical morality is no exception to the cooperative function of moral cognition. It emerges in response to a key feature of cooperation, namely that cooperation is (ultimately) a long-term strategy, requiring (proximately) the self-control of appetites for immediate gratification. Puritanical moralizations condemn behaviors which, although inherently harmless, are perceived as indirectly facilitating uncooperative behaviors, by impairing the self-control required to refrain from cheating. Drinking, drugs, immodest clothing, and unruly music and dance, are condemned as stimulating short-term impulses, thus facilitating uncooperative behaviors (e.g., violence, adultery, free-riding). Overindulgence in harmless bodily pleasures (e.g., masturbation, gluttony) is perceived as making people slave to their urges, thus altering abilities to resist future antisocial temptations. Daily self-discipline, ascetic temperance, and pious ritual observance are perceived as cultivating the self-control required to honor prosocial obligations. We review psychological, historical, and ethnographic evidence supporting this account. We use this theory to explain the fall of puritanism in WEIRD societies, and discuss the cultural evolution of puritanical norms. Explaining puritanical norms does not require adding mechanisms unrelated to cooperation in our models of the moral mind.
Monday, October 03, 2022
Triggers for mother love
A fascinating open source article from Margaret Livingstone carrying forward the famous experiments by Harry Harlow:
Significance
Harry Harlow found that infant monkeys form strong and lasting attachments to inanimate surrogates, but only if the surrogate is soft; here I report that postpartum monkey mothers can also form strong and lasting attachments to soft inanimate objects. Thus, mother/infant and infant/mother bonds may both be triggered by soft touch.Abstract
Previous studies showed that baby monkeys separated from their mothers develop strong and lasting attachments to inanimate surrogate mothers, but only if the surrogate has a soft texture; soft texture is more important for the infant’s attachment than is the provision of milk. Here I report that postpartum female monkeys also form strong and persistent attachments to inanimate surrogate infants, that the template for triggering maternal attachment is also tactile, and that even a brief period of attachment formation can dominate visual and auditory cues indicating a more appropriate target.
Friday, September 30, 2022
Trigger warnings and ‘safety-ism’ don’t work.
Trigger warnings, content warnings, or content notes are alerts about upcoming content that may contain themes related to past negative experiences. Advocates claim that warnings help people to emotionally prepare for or completely avoid distressing material. Critics argue that warnings both contribute to a culture of avoidance at odds with evidence-based treatment practices and instill fear about upcoming content. Recently, a body of psychological research has begun to investigate these claims empirically. We present the results of a meta-analysis of all empirical studies on the effects of these warnings. Overall, we found that warnings have no effect on affective responses to negative material nor on educational outcomes (i.e., comprehension). However, warnings reliably increase anticipatory affect. Findings on avoidance were mixed, suggesting either that warnings have no effect on engagement with material, or that they increase engagement with negative material under specific circumstances. Limitations and implications for policy and therapeutic practice are discussed.Manson also discusses the dying fad of "safety-ism" noted by Jonathan Haidt and Greg Lukianoff in their book "The Coddling of the American Mind," and makes the point that...
The human mind is antifragile—that is, it gains from discomfort and strain. That means to grow stronger, the human mind needs to regularly be confronted with difficult and upsetting experiences to develop stability and serenity for itself.
Wednesday, September 28, 2022
Neural synchronization predicts marital satisfaction
From Li et al.:
Significance
Humans establish intimate social and personal relationships with their partners, which enable them to survive, successfully mate, and raise offspring. Here, we examine the neurobiological basis of marital satisfaction in humans using naturalistic, ecologically relevant, interpersonal communicative cues that capture shared neural representations between married couples. We show that in contrast to demographic and personality measures, which are unreliable predictors of marital satisfaction, neural synchronization of brain responses during viewing of naturalistic maritally relevant movies predicted higher levels of marital satisfaction in couples. Our findings demonstrate that brain similarities that reflect real-time mental responses to subjective perceptions, thoughts, and feelings about interpersonal and social interactions are strong predictors of marital satisfaction and advance our understanding of human marital bonding.Abstract
Marital attachment plays an important role in maintaining intimate personal relationships and sustaining psychological well-being. Mate-selection theories suggest that people are more likely to marry someone with a similar personality and social status, yet evidence for the association between personality-based couple similarity measures and marital satisfaction has been inconsistent. A more direct and useful approach for understanding fundamental processes underlying marital satisfaction is to probe similarity of dynamic brain responses to maritally and socially relevant communicative cues, which may better reflect how married couples process information in real time and make sense of their mates and themselves. Here, we investigate shared neural representations based on intersubject synchronization (ISS) of brain responses during free viewing of marital life-related, and nonmarital, object-related movies. Compared to randomly selected pairs of couples, married couples showed significantly higher levels of ISS during viewing of marital movies and ISS between married couples predicted higher levels of marital satisfaction. ISS in the default mode network emerged as a strong predictor of marital satisfaction and canonical correlation analysis revealed a specific relation between ISS in this network and shared communication and egalitarian components of martial satisfaction. Our findings demonstrate that brain similarities that reflect real-time mental responses to subjective perceptions, thoughts, and feelings about interpersonal and social interactions are strong predictors of marital satisfaction, reflecting shared values and beliefs. Our study advances foundational knowledge of the neurobiological basis of human pair bonding.
Monday, September 26, 2022
How nature nurtures
Since living in cities is associated with an increased risk for mental disorders such as anxiety disorders, depression, and schizophrenia, it is essential to understand how exposure to urban and natural environments affects mental health and the brain. It has been shown that the amygdala is more activated during a stress task in urban compared to rural dwellers. However, no study so far has examined the causal effects of natural and urban environments on stress-related brain mechanisms. To address this question, we conducted an intervention study to investigate changes in stress-related brain regions as an effect of a one-hour walk in an urban (busy street) vs. natural environment (forest). Brain activation was measured in 63 healthy participants, before and after the walk, using a fearful faces task and a social stress task. Our findings reveal that amygdala activation decreases after the walk in nature, whereas it remains stable after the walk in an urban environment. These results suggest that going for a walk in nature can have salutogenic effects on stress-related brain regions, and consequently, it may act as a preventive measure against mental strain and potentially disease. Given rapidly increasing urbanization, the present results may influence urban planning to create more accessible green areas and to adapt urban environments in a way that will be beneficial for citizens’ mental health.A few previous MindBlog posts on this topic:
Blue Mind - looking at water improves your health and calm
Pictures of green spaces make you happier.
More green space in childhood, fewer psychiatric disorders in adulthood.