Friday, November 04, 2022
Senescent cells targeted by anti-aging therapies may not be all bad
Michael Irving does a brief article in New Atlas that points to work by Reyes et al. showing that some senescent od the sort that accumulate with aging not only secrete inflammatory compounds that can be damaging to tisse around them, but also can play a positive role in repairing tissue damage. This suggests that senolytics research should focus on developing drugs that will target specific subsets of senescent cells that are implicated in disease rather than in regeneration.