Wednesday, June 17, 2020

Jon Stewart weighs back in.....

I was struck by bits of clarity in David Marchese's interview of Jon Stewart. The interview was occasioned by the upcoming release of Stewart's satirical new movie "Irresistible." I want to pass on some clips of comments by Stewart that I made for myself:
Twenty-four-hour news networks are built for one thing, and that’s 9/11. There are very few events that would justify being covered 24 hours a day, seven days a week. So in the absence of urgency, they have to create it. You create urgency through conflict.
We continue to make this about the police — the how of it. How can they police? Is it about sensitivity and de-escalation training and community policing? All that can make for a less-egregious relationship between the police and people of color. But the how isn’t as important as the why, which we never address. The police are a reflection of a society. They’re not a rogue alien organization that came down to torment the black community. They’re enforcing segregation. Segregation is legally over, but it never ended. The police are, in some respects, a border patrol, and they patrol the border between the two Americas. We have that so that the rest of us don’t have to deal with it. Then that situation erupts, and we express our shock and indignation. But if we don’t address the anguish of a people, the pain of being a people who built this country through forced labor — people say, ‘‘I’m tired of everything being about race.’’ Well, imagine how [expletive] exhausting it is to live that.
There’s not a white person out there who would want to be treated like even a successful black person in this country. And if we don’t address the why of that treatment, the how is just window dressing. You know, we’re in a bizarre time of quarantine. White people lasted six weeks and then stormed a state building with rifles, shouting: ‘‘Give me liberty! This is causing economic distress! I’m not going to wear a mask, because that’s tyranny!’’ That’s six weeks versus 400 years of quarantining a race of people. The policing is an issue, but it’s the least of it. We use the police as surrogates to quarantine these racial and economic inequalities so that we don’t have to deal with them.
...there’s no oxygen for the campaign other than the oxygen that Trump’s Twitter feed puts into things. And no matter what, Trump has defined the terms of the fight. It’s going to be: What is America’s greatness? You have to fight on those terms, and that’s an opportunity to define what you believe is our greatness. Now, that’s not to say the political consultants won’t say to Biden, ‘‘You need to define your own lane.’’ But he doesn’t. The road is built.
What is broken about Washington isn’t the bureaucracy. It’s legislators’ ability to address the issues inherent in any society — and the reason they can’t address them is that when you have a duopoly, there is no incentive to work together to create something better. Plus, you have one party whose premise is that government is bad and whose goal is to prove that, which makes them, in essence, a double agent. All these things coalesce to make problem-solving the antithesis of what we’ve created. We’re incentivized for more extreme candidates, for more extreme partisanship, for more conflict and permanent campaigning, for corporate interests to have more influence on the process, not less.
‘‘The Daily Show’’ was a critique of the news and a critique of those systems [News intertwined with Entertainment]. If they’d taken in what we were saying, they wouldn’t be doing what they’re doing now: creating urgency through conflict. Conflict has become the catalyst for the economic model. The entire system functions that way now. We are two sides — in a country of 350 million people.
I don’t think it [the news media] has ever had a good handle on a political moment. It’s not designed for that. It’s designed for engagement. It’s like YouTube and Facebook: an information-laundering perpetual-radicalization machine. It’s like porn. I don’t mean that to be flip...The algorithm is not designed for thoughtful engagement and clarity. It’s designed to make you look at it longer.
The media’s job is to deconstruct the manipulation, not to just call it a lie. It’s about informing on how something works so that you understand the lie’s purpose. What are the structural issues underneath the lie? The media shouldn’t take the political system personally, or allow its own narcissism to rise to the narcissism of the politicians, or become offended that the politicians are lying — their job is to manipulate.
...I think he [Trump] understands very well — and the right understands very well — that undermining the credibility of the institutions that people look to for help defining and making sense of reality is the key to bending reality to your will. It’s a wonderful rhetorical trick. He had a great one on Memorial Day weekend:‘‘We’re getting great reviews on our pandemic response. But of course, not getting credit for it.’’ The twisted logic of that: If you’re getting great reviews, I’m pretty sure that’s considered credit. It’s like saying, ‘‘I’m being praised, but of course I won’t be praised for it.’’ Language is utterly meaningless. Everything is placed into its category in the tribal war and who its real victims are: Donald Trump and his minions. Poor little billionaire president who can’t catch a break. It’s incredible. Are we all just extras in this guy’s movie? But I do feel as if his approach has worked for him his whole life.
There’s all this talk of being on the right side of history, but what does that mean? ‘‘The arc of moral universe is long, but it bends toward justice.’’ Who’s bending it? What are we doing to further that? If you just get rid of Trump, that doesn’t end this. It’s too easy to say: ‘‘I support this other guy. Therefore, I’m part of the solution.’’ Or: ‘‘You support that guy. Therefore, you’re the problem.’’ Now, that is in no way exculpatory to the supporters of those policies or that regime. My point was: What does that judgment get you? What is the accountability that we have for those who really do believe this is unjust but still accept the tacit societal arrangements?
...the view we get of the country is not accurate. We get the artifice of it, the conflict of it. I’m not naïve. I don’t think that true divisions and animosities and bigotry and prejudices don’t exist. We see that every day. But fundamentally, we are a resilient and strong and resourceful nation that has oftentimes overcome our worst tendencies — ‘‘overcome’’ is probably too strong a word. But our biggest problem as humans is ignorance, not malevolence. Ignorance is an entirely curable disease...You need to talk to people. Ignorance is often cured by experience, by spending time with what you don’t understand...In the same way that Trump’s recklessness is born out of experience, so is my optimism, because good people outweigh [expletive] people. By a long shot.

Tuesday, June 16, 2020

Rich and Poor

San Paulo, Brazil.

Motion aftereffect demonstration

I'm passing this on, a rather powerful (practically hallucinatory) demonstration. Look at the center of the moving lines for 20 seconds and then at a picture on the wall. DO NOT TRY THIS IF YOU HAVE PHOTOSENSITIVE EPILEPSY!

Monday, June 15, 2020

As diversity increases, people paradoxically perceive social groups as more similar

From Bai et al.:

Significance
Globalization and immigration expose people to increased diversity, challenging them to think in new ways about new people. Yet, scientists know little about how changing demography affects human mental representations of social groups, relative to each other. How do mental maps of stereotypes differ, with exposure to diversity? At national, state, and individual levels, more diversity is associated with less stereotype dispersion. Paradoxically, people produce more-differentiated stereotypes in ethnically homogeneous contexts but more similar, overlapping stereotypes in diverse contexts. Increased diversity and decreased stereotype dispersion correlate with subjective wellbeing. Perhaps human minds adapt to social diversity, by changing their symbolic maps of the array of social groups, perceiving overlaps, and preparing for positive future intergroup relations. People can adjust to diversity.
Abstract
With globalization and immigration, societal contexts differ in sheer variety of resident social groups. Social diversity challenges individuals to think in new ways about new kinds of people and where their groups all stand, relative to each other. However, psychological science does not yet specify how human minds represent social diversity, in homogeneous or heterogenous contexts. Mental maps of the array of society’s groups should differ when individuals inhabit more and less diverse ecologies. Nonetheless, predictions disagree on how they should differ. Confirmation bias suggests more diversity means more stereotype dispersion: With increased exposure, perceivers’ mental maps might differentiate more among groups, so their stereotypes would spread out (disperse). In contrast, individuation suggests more diversity means less stereotype dispersion, as perceivers experience within-group variety and between-group overlap. Worldwide, nationwide, individual, and longitudinal datasets (n = 12,011) revealed a diversity paradox: More diversity consistently meant less stereotype dispersion. Both contextual and perceived ethnic diversity correlate with decreased stereotype dispersion. Countries and US states with higher levels of ethnic diversity (e.g., South Africa and Hawaii, versus South Korea and Vermont), online individuals who perceive more ethnic diversity, and students who moved to more ethnically diverse colleges mentally represent ethnic groups as more similar to each other, on warmth and competence stereotypes. Homogeneity shows more-differentiated stereotypes; ironically, those with the least exposure have the most-distinct stereotypes. Diversity means less-differentiated stereotypes, as in the melting pot metaphor. Diversity and reduced dispersion also correlate positively with subjective wellbeing.

Friday, June 12, 2020

The psyche is not inside us but between us.

I want to pass on a few clips from an article by psychotherapist James Barnes on the work and ideas of Donald Winnicott (1896-1971), a central figure in mid-20th-century psychoanalysis, whose theory was:

...radically at odds with the Freudian model and indeed the models employed by modern psychiatry and cognitive behavioural therapy (CBT)...he saw the area in between self and other as the proper domain of mental life and the place where it develops. He largely circumvented the subject-object dualism inherent in the Freudian model of mind (which both the Ego-psychologists and the Kleinians subscribed to) and espoused, or at least regularly insinuated, a fundamentally unitary conception of self and other...Freud and the schools that followed him saw any apparent continuity of self and other – an experience common to the infant, ‘psychotics’ and ‘regressed patients’ alike – as a narcissistic delusion that had to be confronted. By taking the continuity of self and other seriously, Winnicott flipped this picture on its head. He thought of it, in fact, as primary.

Winnicott believed that separate minds give way to experiential units – that subjects with minds emerge out of the domain of interpersonal relations: the ‘social matrix of psyche’... Thus, far from being separate, closed-off entities that somehow manage to figure out each other externally, we are, according to Winnicott, radically open beings in immediate contact with each other.

Winnicott expressed this idea enigmatically when he said: ‘There is no such thing as a baby … if you set out to describe a baby, you will find you are describing a baby and someone.’ His perspective is most relevant for understanding a baby’s experience with her parents, but it’s at the core of all experience, even though we don’t usually recognise it as such. Experience of the world and others is the primary given, and minds – rather than traversing an existing separation – are in a certain sense responsible for creating it. Effectively, this is an inversion of Freud’s dualistic model.

Winnicott’s divergence from subject-object dualism is perhaps most clearly illustrated by his firm belief that we never extricate ourselves from this transitional realm and its subject-object mix-up – nor would we want to. For Freud, and for reductive psychiatry and CBT alike, there is a fundamental assumption that objective states of affairs in an independent world are the basic truth of experience. Indeed, the models rise and fall with the veracity of this picture.

However, Winnicott had a very different vision. He wrote of culture – its artifacts and its activities – as extensions of the transitional phenomena of childhood, themselves rooted in the original mix-up with the parent. He thought that the very worlds we inhabit and take for granted are always partly of our own making. For Winnicott, it is only because the worlds we experience are coextensive with ourselves that they feel alive, alluring and psychically experienceable in the first instance, rather than like cold, mathematical structures, as scientific materialism would have us believe. In this way, Winnicott’s psychological paradox of subject and object becomes a philosophical paradox of idealism and materialism...These fundamental views now lie at the heart of what’s known in modern parlance as relational and intersubjective depth psychotherapy.

Barnes proceeds to argue that the one-person psychologies of the Freudian and cognitive behavioral therapy models have caused social damage, and that we would do well to go:

...back to Winnicott - to his vision of the psyche as intimately interpersonal and social in nature; to his centralisation of interpersonal trauma and deficit at the root of our suffering; and to his profound insights into the area in between, which come into focus when we do so.













Thursday, June 11, 2020

Making Us/Them Dichotomies More Benign.

I'm reposting this item from 2016 as particularly relevant to the present.... Interesting thoughts from Robert Sapolsky:
A truly discouraging thing to me is how easily humans see the world as dichotomized between Us and Them. This comes through in all sorts of ways —social anthropology, lord of the flies, prison experiments, linguistics (all those cultures where the word for the members of that culture translates into "People," thus making a contrast with the non-people living in the next valley). 
As a neurobiologist, I'm particularly impressed with and discouraged by one finding relevant to this. There's a part of the brain called the amygdala that has lots to do with fear and anxiety and aggression. Functional brain imaging studies of humans show that the amygdala becomes metabolically active when we look at a scary face (even when the face is flashed up so quickly that we aren't consciously aware of seeing it). And some recent work—solid, done by top people, independently replicated — suggests that the amygdala can become activated when we view the face of someone from another race. The Them as scary, and the Them being someone whose skin color is real different from our own. 
Damn, that's an upsetting finding. 
But right on the heels of those studies are follow-ups showing that the picture is more complicated. The "Other skin color = scared activated amygdala = the Other" can be modified by experience. "Experience," can be how diverse of a world you grew up in. More diversity, and the amygdala is likely to become activated in that circumstance. And also, "experience," can be whether, shortly before your amygdala is put through the brain imaging paces, you are subtly biased to think about people categorically or as individuals. If you're cued towards individuating, your amygdala doesn't light up. 
Thus, it seems quite plausible to me that we are hard-wired towards making Us/Them distinctions and not being all that nice to the Them. But what is anything but hard-wired is who counts as an Us and as a Them —we are so easily manipulated into changing those categories. 
So, I'm optimistic that with the right sort of priorities and human engineering (whatever that phrase means), we can be biased towards making Us/Them dichotomies far more benign than they tend to be now. Say, by making all of us collectively feel like an Us with Them being the space aliens that may attack us some day. Or making the Them to be mean, shitty, intolerant people without compassion. 
But, I'm sure not optimistic that we'll soon be having political, religious or cultural leaders likely to move us effectively in that direction. Just to deflate that optimism.

Wednesday, June 10, 2020

A perky bit of piano - Haydn Fantasia in C major, glitches included

I've generated almost 5,000 posts since this blog started in 2016 (before the first iPhone was released in 2017!, seems an aeon ago.) As a diversion during my self isolation until proper testing or a vaccine appears for COVID-19, I'm scanning through these posts from their beginning, and will be passing on a few. Coming across this bit of my piano playing perked me up yesterday, and I pass it on here, a Haydn fantasia.

Tuesday, June 09, 2020

People aged 95 and older show stronger brain connectivity

Jiyang et al. have used resting-state functional MRI to compare 57 individuals aged 95-103 years old with 66 cognitively unimpaired younger participants aged 76-79. The centenarians showed more synchronized activation of left and right fronto-parietal control networks. Their abstract:

Highlights

We studied functional connectivity (FC) in near-centenarians and centenarians (nCC).

NCC showed stronger FC between bilateral frontoparietal control network (FPCN).

The stronger bilateral FPCN FC was linked to better visuospatial ability in nCC.

Abstract

Centenarians without dementia can be considered as a model of successful ageing and resistance against age-related cognitive decline. Is there something special about their brain functional connectivity that helps them preserve cognitive function into the 11th decade of life? In a cohort of 57 dementia-free near-centenarians and centenarians (95–103 years old) and 66 cognitively unimpaired younger participants (76–79 years old), we aimed to investigate brain functional characteristics in the extreme age range using resting-state functional MRI. Using group-level independent component analysis and dual regression, results showed group differences in the functional connectivity of seven group-level independent component (IC) templates, after accounting for sex, education years, and grey matter volume, and correcting for multiple testing at family-wise error rate of 0.05. After Bonferroni correction for testing 30 IC templates, near-centenarians and centenarians showed stronger functional connectivity between right frontoparietal control network (FPCN) and left inferior frontal gyrus (Bonferroni-corrected p ​= ​0.024), a core region of the left FPCN. The investigation of between-IC functional connectivity confirmed the voxel-wise result by showing stronger functional connectivity between bilateral FPCNs in near-centenarians and centenarians compared to young-old controls. In addition, near-centenarians and centenarians had weaker functional connectivity between default mode network and fronto-temporo-parietal network compared to young-old controls. In near-centenarians and centenarians, stronger functional connectivity between bilateral FPCNs was associated with better cognitive performance in the visuospatial domain. The current study highlights the key role of bilateral FPCN connectivity in the reserve capacity against age-related cognitive decline.

Monday, June 08, 2020

How Covid-19 stress scrambles our brains

The pandemic is providing an opportunity for a massive, real-time experiment on stress.  Even mild stress can impair the activities of the prefrontal cortex areas 'executive' functions that regulate our attentional focus and emotions. When this area grows more quiet more reactionary brain networks that it normally inhits (centering on the amygdalae) are unleashed. You should read the article by Laura Sanders that describes, with clear illustrations, experiments showing how our thoughtful planning activities are disrupted by stress.

Friday, June 05, 2020

Confront your decline head on.

I pass on another of Arthur Brook's biweekly essays in the Atlantic. This one notes that Much like contemplating death can neutralize the fear of it, it can help to acclimate yourself to the idea of losing professional skills before it happens. After describing the meditation called maranasati ("mindfulness of death") that consists of imagining nine states of one's own dead body, he offers a corresponding list to deal with decline...
I feel my competence declining.
Those close to me begin to notice that I am not as sharp as I used to be.
Other people receive the social and professional attention I used to receive.
I have to decrease my workload and step back from daily activities I once completed with ease.
I am no longer able to work.
Many people I meet do not recognize me or know me for my previous work.
I am still alive, but professionally I am no one.
I lose the ability to communicate my thoughts and ideas to those around me.
I am dead, and I am no longer remembered at all for my accomplishments.
The fear of death is much worse when it is an amorphous phantasm—something lurking menacingly in the shadows—than when it is a plain reality. And so it is with decline. Unacknowledged, it is scary. Acknowledged and contemplated, it can become a normal, natural part of life’s cadence.
It is true that Western society glorifies youthful beauty and the machinelike efficiency of homo economicus. But you don’t have to play along with our culture’s neurotic exercise in futility. Become the master who, when your social or professional standing is threatened by age or circumstance, says, “Don’t you see that I am a person who could be utterly forgotten without batting an eye?”

Thursday, June 04, 2020

Do you really want to make your own complex medical decisions?


Over the past several decades, the United States medical system has increasingly prioritized patient autonomy. Physicians routinely encourage patients to come to their own decisions about their medical care rather than providing patients with clearer yet more paternalistic advice. Although political theorists, bioethicists, and philosophers generally see this as a positive trend, the present research examines the important question of how patients and advisees in general react to full decisional autonomy when making difficult decisions under uncertainty. Across six experiments (N = 3,867), we find that advisers who give advisees decisional autonomy rather than offering paternalistic advice are judged to be less competent and less helpful. As a result, advisees are less likely to return to and recommend these advisers and pay them lower wages. Importantly, we also demonstrate that advisers do not anticipate these effects. We document these results both inside and outside the medical domain, suggesting that the preference for paternalism is not unique to medicine but rather is a feature of situations in which there are adviser–advisee asymmetries in expertise. We find that the preference for paternalism holds when advice is solicited or unsolicited, when both paternalism and autonomy are accompanied by expert guidance, and it persists both before and after the outcomes of paternalistic advice are realized. Lastly, we see that the preference for paternalism only occurs when decision makers perceive their decision to be difficult. These results challenge the benefits of recently adopted practices in medical decision making that prioritize full decisional autonomy.


Wednesday, June 03, 2020

Anxiolytic actions of oxytocin, unlike those of benzodiazepines, involve brain regions outside the amygdala


Significance

A potential new target for anxiolytic drug development is the oxytocin (OXT) neuropeptide system. An emerging question is whether OXT has similar effects on the neural microcircuitry of fear compared with clinically established compounds such as benzodiazepines. The present functional MRI study showed that both OXT and its benzodiazepine comparator lorazepam (LZP) reduced centromedial amygdala responses to fear signals. OXT, but not LZP, increased extra-amygdalar connectivity between the centromedial amygdala and frontoparietal regions. Thus, while both compounds inhibited the centromedial amygdala, OXT, but not LZP, elicited large-scale connectivity changes of potential therapeutic relevance.

Abstract

Benzodiazepines (BZDs) represent the gold standard of anxiolytic pharmacotherapy; however, their clinical benefit is limited by side effects and addictive potential. Consequently, there is an urgent need to develop novel and safe anxiolytics. The peptide hormone oxytocin (OXT) exhibits anxiolytic-like properties in animals and humans, but whether OXT and BZDs share similar effects on the neural circuitry of fear is unclear. Therefore, the rationale of this ultra-high-field functional MRI (fMRI) study was to test OXT against the clinical comparator lorazepam (LZP) with regard to their neuromodulatory effects on local and network responses to fear-related stimuli. One hundred twenty-eight healthy male participants volunteered in this randomized double-blind, placebo-controlled, between-group study. Before scanning using an emotional face-matching paradigm, participants were randomly administered a single dose of OXT (24 IU), LZP (1 mg), or placebo. On the behavioral level, LZP, but not OXT, caused mild sedation, as evidenced by a 19% increase in reaction times. On the neural level, both OXT and LZP inhibited responses to fearful faces vs. neutral faces within the centromedial amygdala (cmA). In contrast, they had different effects on intra-amygdalar connectivity; OXT strengthened the coupling between the cmA and basolateral amygdala, whereas LZP increased the interplay between the cmA and superficial amygdala. Furthermore, OXT, but not LZP, enhanced the coupling between the cmA and the precuneus and dorsomedial prefrontal cortex. These data implicate inhibition of the cmA as a common denominator of anxiolytic action, with only OXT inducing large-scale connectivity changes of potential therapeutic relevance.

Tuesday, June 02, 2020

Your voice carries information about your upper body movements.

Fascinating observations by Pouw et al.:
Significance
We show that the human voice carries an acoustic signature of muscle tensioning during upper limb movements which can be detected by listeners. Specifically, we find that human listeners can synchronize their own movements to very subtle wrist movements of a vocalizer only by listening to their vocalizations and without any visual contact. This study shows that the human voice contains information about dynamic bodily states, breaking ground for our understanding of the evolution of spoken language and nonverbal communication. The current findings are in line with other research on nonhuman animals, showing that vocalizations carry information about bodily states and capacities.
Abstract
We show that the human voice has complex acoustic qualities that are directly coupled to peripheral musculoskeletal tensioning of the body, such as subtle wrist movements. In this study, human vocalizers produced a steady-state vocalization while rhythmically moving the wrist or the arm at different tempos. Although listeners could only hear and not see the vocalizer, they were able to completely synchronize their own rhythmic wrist or arm movement with the movement of the vocalizer which they perceived in the voice acoustics. This study corroborates recent evidence suggesting that the human voice is constrained by bodily tensioning affecting the respiratory–vocal system. The current results show that the human voice contains a bodily imprint that is directly informative for the interpersonal perception of another’s dynamic physical states.

Monday, June 01, 2020

An "Apostle's Creed" for the humanistic scientific materialist?


(Note: I have begun to slowly go though the posts on MindBlog, which began in Feb. of 2006, over 14 years ago.  Here I repeat the post that appeared on March 14, 2006.  I could have written it yesterday, without changing a word.)

The classical Christian apostle's creed, over 1600 years old and formulated soon after the writing of the New Testament, is a series of "I believe....." statements. Without thinking too much about it, I've decided to quickly write down a few sentences to suggest the very different creed that I follow. Here they are:

I believe the most fundamental content of our minds to be the sensed physical breathing and moving body, a quiet awareness that underlies our surface waves of emotions and thoughts.

I believe that this awareness can begin to experience a larger process, closer to the machinery that is generating a self, a process that observes rather than being completely defined by the current narrative "I" chatter of who-I-am or what-it-is-I-do.

I believe that this awareness can expand to feel its part in a a drama of evolving life on this planet and an evolving universe - a theater much more universal than conventional cultural or religious myths.

I believe that this awareness can enhance the depth, sanity, and sensed completion of each moment. It provides a sense of wholeness and sufficiency from which actions rise. It makes contact with other humans more sane and whole.

Friday, May 29, 2020

Brain connectivity fingerprinting of complex human personality traits - another tool for the surveillance state?

A group of researchers in the Department of Radiology, Anhui Medical University, Hefei, China, find that resting-state functional connectivity patterns of whole-brain large-scale networks can effectively and reliably predict complex human personality traits, including agreeableness, openness, conscientiousness and neuroticism, at the individual level. Fascinating work, but one wonders whether this might become yet another tool that might be used by a government to assess its citizens? :
Neuroimaging studies have linked inter-individual variability in the brain to individualized personality traits. However, only one or several aspects of personality have been effectively predicted based on brain imaging features. The objective of this study was to construct a reliable prediction model of personality in a large sample by using connectome-based predictive modeling (CPM), a recently developed machine learning approach. High-quality resting-state functional magnetic resonance imaging data of 810 healthy young participants from the Human Connectome Project dataset were used to construct large-scale brain networks. Personality traits of the five-factor model (FFM) were assessed by the NEO Five Factor Inventory. We found that CPM successfully and reliably predicted all the FFM personality factors (agreeableness, openness, conscientiousness and neuroticism) other than extraversion in novel individuals. At the neural level, we found that the personality-associated functional networks mainly included brain regions within default mode, frontoparietal executive control, visual and cerebellar systems. Although different feature selection thresholds and parcellation strategies did not significantly influence the prediction results, some findings lost significance after controlling for confounds including age, gender, intelligence and head motion. Our finding of robust personality prediction from an individual’s unique functional connectome may help advance the translation of ‘brain connectivity fingerprinting’ into real-world personality psychological settings.

Thursday, May 28, 2020

An explanation for human synesthesia

Fascinating work from Maurer et al.:
Synesthesia is a neurologic trait in which specific inducers, such as sounds, automatically elicit additional idiosyncratic percepts, such as color (thus “colored hearing”). One explanation for this trait—and the one tested here—is that synesthesia results from unusually weak pruning of cortical synaptic hyperconnectivity during early perceptual development. We tested the prediction from this hypothesis that synesthetes would be superior at making discriminations from nonnative categories that are normally weakened by experience-dependent pruning during a critical period early in development—namely, discrimination among nonnative phonemes (Hindi retroflex /d̪a/ and dental /ɖa/), among chimpanzee faces, and among inverted human faces. Like the superiority of 6-mo-old infants over older infants, the synesthetic groups were significantly better than control groups at making all the nonnative discriminations across five samples and three testing sites. The consistent superiority of the synesthetic groups in making discriminations that are normally eliminated during infancy suggests that residual cortical connectivity in synesthesia supports changes in perception that extend beyond the specific synesthetic percepts, consistent with the incomplete pruning hypothesis.

Wednesday, May 27, 2020

Social animals need connection for health and survival

Snyder-Mackler et al. have reviewed the relationships between social environment and many aspects of health and well-being across nonhuman mammals and investigated the similarities between these and patterns in humans. They found many of the same threats and responses across social mammals.

From their introduction:
The relationship between the social environment and mortality risk has been known in humans for some time, but studies in other social mammals have only recently been able to test for the same general phenomenon. These studies reveal that measures of social integration, social support, and, to a lesser extent, social status independently predict life span in at least four different mammalian orders. Despite key differences in the factors that structure the social environment in humans and other animals, the effect sizes that relate social status and social integration to natural life span in other mammals align with those estimated for social environmental effects in humans. Also like humans, multiple distinct measures of social integration have predictive value, and in the taxa examined thus far, social adversity in early life is particularly tightly linked to later-life survival.
Animal models have also been key to advancing our understanding of the causal links between social processes and health. Studies in laboratory animals indicate that socially induced stress has direct effects on immune function, disease susceptibility, and life span. Animal models have revealed pervasive changes in the response to social adversity that are detectable at the molecular level. Recent work in mice has also shown that socially induced stress shortens natural life spans owing to multiple causes, including atherosclerosis. This result echoes those in humans, in which social adversity predicts increased mortality risk from almost all major causes of death.
A comparative perspective on the social determinants of health (click to enlarge).

Tuesday, May 26, 2020

The obsolescence of three core operating systems that have shaped civilization for the past 350 years

I want to pass on a quotations from the beginning and end of Roger Cohen's essay on how honestly - on the 75th anniversary of the end of World War II in Europe - Germany is facing its fractured past:
“The nation-state alone does not have a future,” Angela Merkel, the German chancellor, said this week. It was a direct challenge to President Trump’s “America First,” the slogan whose poison keeps on giving. His United States has become the most unserious of nations.
Stephen Heintz, the president of the Rockefeller Brothers Fund, has written of a crisis “that stems from the growing obsolescence of three core operating systems that have shaped civilization for the past 350 years: capitalism, fueled by carbon since the dawn of the Industrial Age and increasingly driven by global financialization; the nation-state system, formalized by the Treaty of Westphalia in 1648; and representative democracy, a system of self-rule based on Enlightenment ideals of freedom, fairness, justice and equality.”
The problem is that “our practice of capitalism is both putting the planetary ecosystem at risk and generating vast economic inequality.” The nation-state is “inadequate for managing transnational challenges like global warming.” And “representative democracy is neither truly representative nor very democratic as citizens feel that self-rule has given way to rule by corporations, special interests and the wealthy.”
The virus and accompanying economic collapse have only redoubled the urgency of these reflections. This is the Age of Undoing — of world order, of international law, of truth, of America’s word. It is a dangerous time, as Germany knows better than any nation. Autocracy feeds on fear, misery, resentment and lies. It did in the 1930s; it does now. Better to love your country with a broken heart than to love it blind.

Monday, May 25, 2020

Rules for identifying your life's work.

During this time of virtual or postponed college graduations, Arthur Brooks does a relevant installment in his bi-weekly series for Atlantic Magazine. I'm going to pass on just sentence or two of each of his rules for graduates in finding your calling, and suggest you read the whole article:  

Rule 1. The work has to be the reward.
One of the biggest mistakes people make in their careers is to treat work primarily as a means to an end. Whether that end is money, power, or prestige, this instrumentalization of work leads to unhappiness.
Rule 2. An interesting career is better than a fun career.
Interest is considered by many neuroscientists to be a positive primary emotion, processed in the limbic system of the brain. Something that truly interests you is intensely pleasurable; it also must have meaning in order to hold your interest. Thus, “Is this work deeply interesting to me?” is a helpful litmus test of [for] a job.
Rule 3. A career doesn’t have to be a straight line.
Scholars at the University of Southern California have studied career patterns and come up with four broad categories. The first are linear careers, which climb steadily upward, with everything building on everything else...There are three others. Steady-state careers involve staying at one job and growing in expertise. Transitory careers are ones in which people jump from job to job or even field to field, looking for new challenges. Spiral careers, the last category, are more like a series of mini careers—people spend many years developing in a profession, then shift fields seeking not just for novelty, but for work that builds on the skills of their previous mini careers.
Rule 4. Beware of unhealthy passions.
This rule refines Rule 3. Yes, look for something in which you are intensely interested. But go further and ask, “Is my interest obsessive, or harmonious? Does this job or career bring out the best in me? Does it make me a happier, better person, or, in pursuing it, am I neglecting other important things life has to offer?”

Friday, May 22, 2020

AI for social good: Well meaning gobbledegook

I pass on this link to a my-eyes-glaze-over open access perspective on international efforts to use artificial intelligence for social good. The effort is a noble one, and indeed tries to deal with a very complex domain. Here is the abstract, which introduces the first of an array of acronyms:
Advances in machine learning (ML) and artificial intelligence (AI) present an opportunity to build better tools and solutions to help address some of the world’s most pressing challenges, and deliver positive social impact in accordance with the priorities outlined in the United Nations’ 17 Sustainable Development Goals (SDGs). The AI for Social Good (AI4SG) movement aims to establish interdisciplinary partnerships centred around AI applications towards SDGs. We provide a set of guidelines for establishing successful long-term collaborations between AI researchers and application-domain experts, relate them to existing AI4SG projects and identify key opportunities for future AI applications targeted towards social good.
Added note: I almost never respond positively to emails requesting that I link to a particular advocacy or commercial site, but I make an exception on receiving this morning email on 8/12/2020:
My name is Sean from Don’t Panic. We’re a Creative Advertising agency in London passionate about creating cause-related advertising campaigns for charities and brands.
I am a fan of your website and I noticed that you linked to a Nature resource discussing social good on this page https://mindblog.dericbownds.net/2020/05/ai-for-social-good-well-meaning.html.
I have put together an article exploring what social good is. I think that your readers would find this very useful. You can find it here: https://www.dontpaniclondon.com/what-is-social-good/
I’d be very grateful if you considered linking to my article in addition to the Nature resource.