Here is a totally fascinating study
done at the University College Cork indicating that the presence of probiotic bacteria in the gut can result in lower stress in the brain (via a pathway involving the vagus nerve and the brain neurotransmitter GABA). Perhaps that’s one reason for the longevity observed in many yogurt-eating populations. Their
...findings highlight the important role of bacteria in the bidirectional communication of the gut–brain axis and suggest that certain organisms may prove to be useful therapeutic adjuncts in stress-related disorders such as anxiety and depression.
I've started having organic yoghurt with mixes of different probiotic bacteria such as the Lactobacillus mentioned below for lunch (not the usual supermarket stuff larded with high fructose corn syrup), and of course am feeling more calm already (placebo effect, anyone?). Here is the whole abstract that notes the brain chemistry involved:
There is increasing, but largely indirect, evidence pointing to an effect of commensal gut microbiota on the central nervous system (CNS). However, it is unknown whether lactic acid bacteria such as Lactobacillus rhamnosus could have a direct effect on neurotransmitter receptors in the CNS in normal, healthy animals. GABA is the main CNS inhibitory neurotransmitter and is significantly involved in regulating many physiological and psychological processes. Alterations in central GABA receptor expression are implicated in the pathogenesis of anxiety and depression, which are highly comorbid with functional bowel disorders. In this work, we show that chronic treatment with L. rhamnosus (JB-1) induced region-dependent alterations in GABAB1b mRNA in the brain with increases in cortical regions (cingulate and prelimbic) and concomitant reductions in expression in the hippocampus, amygdala, and locus coeruleus, in comparison with control-fed mice. In addition, L. rhamnosus (JB-1) reduced GABAAα2 mRNA expression in the prefrontal cortex and amygdala, but increased GABAAα2 in the hippocampus. Importantly, L. rhamnosus (JB-1) reduced stress-induced corticosterone and anxiety- and depression-related behavior. Moreover, the neurochemical and behavioral effects were not found in vagotomized mice, identifying the vagus as a major modulatory constitutive communication pathway between the bacteria exposed to the gut and the brain. Together, these findings highlight the important role of bacteria in the bidirectional communication of the gut–brain axis and suggest that certain organisms may prove to be useful therapeutic adjuncts in stress-related disorders such as anxiety and depression.
In the southern part of India all meals end with, usually rice taken with home-made curd (= yogurt). In one western state, people drink lot of buttermilk (curd mixed with water and skimmed to remove fat). These traditions are very ancient.ReplyDelete
Now I know why yoghurts could give me soothing and relaxing effect. All I though because of its taste, yet there is a clear explanation for that. Thanks for sharing.ReplyDelete