Wednesday, January 24, 2024

The Neurobiology of Stress: Vulnerability, Resilience, and Major Depression

A valuable trove of open source articles is provided in the Special Feature section of the Dec. 5 issue of PNAS with an introductory article by Akil and Nestler with the title of this post.  The special feature:

...explores the consequences of the broad-scale increase in psychological stress and the evidence that we are facing a second pandemic of depression, anxiety, and other stress-related disorders. The authors of this feature describe challenges faced and scientific advances being made, spanning animal models to human translation, to illustrate new tools and techniques currently being deployed in understanding the biology of stress and resilience and the interplay between genetic and environmental variables.

1 comment:

  1. Anonymous10:09 AM

    in psychological stress and mental health challenges has far-reaching implications. The insights gained from understanding the biology of stress and resilience can inform interventions and treatment strategies for depression and other mental illnesses. By recognizing the interconnectedness of these issues and advancing our understanding of the underlying mechanisms, I would like to add to work an article which I read recently on depression, we can work towards more effective prevention and management of depression and related disorders.