Most Viewed MindBlog posts...

I occasionally check Feedburner.com to observe web traffic to this blog, and pulled up the following list of most viewed posts. The left column indicates the number of views and the right indicates clicks on links in the post. Entering a few words of the title in the "Search MindBlog" box gets you to a given post...

Non-materialist neuroscience

Here is an discussion on what the authors call the latest installment of the war on science. From their introduction:

Non-materialist neuroscience is the latest front in the war on science. The battle has been a long time coming and it is surprising it has taken so long to get going. Modern neuroscience is rapidly reducing much of human thought, emotion and behavior into component pieces of neuronal interactions. The combination of computational modeling and non-invasive imaging of living brains has allowed researchers to begin describing how complex thought emerges from the firing patterns of neurons. In a way neuroscience is the death knell of dualism. When materialist causes become both necessary and sufficient to explain all of human thought then parsimony dictates that references to a soul or other supernatural entities can be tossed out.

Non-materialist neuroscience is a reaction to these discoveries, a rallying cry for dualism. Like creationism and intelligent design this "new" neuroscience is a reactionary movement against science. Rather than a hypothesis that leads to predictions and experiments, it is simply a catalog of things modern neuroscience supposedly cannot yet explain.

Unsurprisingly, the movement is spear-headed by intelligent design lackeys from the Discovery Institute and related affiliates. The primary proponents of the movement are Michael Egnor, a neurosurgeon and recent contributor to the Discovery Institute blog, Denyse O'Leary a Canadian "journalist" who runs her own blog dedicated to non-materialist neuroscience and likes to copy and paste these entries over on William Dembski's blog as well, and Mario Beauregard the author with O'Leary of a recent book on the subject of non-materialist neuroscience The Spiritual Brain: A Neuroscientist's Case for the Existence of the Soul.

Musicians have enhanced subcortical processing

Musical training is known to modify cortical organization. Musacchia et al. show that:

...such modifications extend to subcortical sensory structures and generalize to processing of speech. Musicians had earlier and larger brainstem responses than nonmusician controls to both speech and music stimuli presented in auditory and audiovisual conditions, evident as early as 10 ms after acoustic onset. Phase-locking to stimulus periodicity, which likely underlies perception of pitch, was enhanced in musicians and strongly correlated with length of musical practice. In addition, viewing videos of speech (lip-reading) and music (instrument being played) enhanced temporal and frequency encoding in the auditory brainstem, particularly in musicians. These findings demonstrate practice-related changes in the early sensory encoding of auditory and audiovisual information.

Do you need more hassles?

Try out this.

Some rambling on "Selves" and "Purpose"

The recent posts on Alwyn Scott and the Blakesless' book prompt me to this random walk....

Self conscious "Purpose" of the sort we humans experience, in the service of crafting new political movements or environments, is an evolved psychology that (sometimes) helps pass on our genes, and requires our distinctively human self reflective "I". Our behavior and that of other animals also reflects a kind of purpose that has been formed by our evolutionary and developmental history. In other animals such behaviors are acted out on the cusp of an eternal present - there is no evidence that they "know that they know" in the way that we can.

Both modern neuroscience (cf. the quote from the Blakesless' book) and Buddhist psychology inform us that the self and the purpose that each of us experiences is an illusion or confabulation of our brains - hopefully a useful one - whose utility is tested by how it enhances our energy and individual survival. This 'illusion' is a powerful instrument of downward causation, regulating our psychological, immune, neuro-endocrine robustness.

What is especially amazing is that our human body/brain can sometimes use meditative or other techniques to bootstrap to a level of metacognition that rests antecedent to - and can be the detached observer of - the generation of this illusion of a self and its purposes.

The maximum power of our self illusion, for most of us, goes with our heartfelt immersion and belief in it (i.e., our delusion). From such a immersion, it can be more difficult to discern or appreciate the different selves and purposes of other humans, and their cultures and historical eras.

Rich and Poor

San Paulo, Brazil.

Playing Action Video Games Reduces Gender Differences in Spatial Cognition

From Feng, Spence, and Pratt (PDF here):

We demonstrate a previously unknown gender difference in the distribution of spatial attention, a basic capacity that supports higher-level spatial cognition. More remarkably, we found that playing an action video game can virtually eliminate this gender difference in spatial attention and simultaneously decrease the gender disparity in mental rotation ability, a higher-level process in spatial cognition. After only 10 hr of training with an action video game, subjects realized substantial gains in both spatial attention and mental rotation, with women benefiting more than men. Control subjects who played a non-action game showed no improvement. Given that superior spatial skills are important in the mathematical and engineering sciences, these findings have practical implications for attracting men and women to these fields.

From their article:

The experimental group was trained using Medal of Honor: Pacific Assault, which was chosen because it is similar to the games typically played by players in Experiment 1 [note: which compared students based on their self reports of game use] and because it has been used before in attention training studies. This game is a 3-D first-person shooter game that requires intense visual monitoring and attentional resources. The control group played Ballance, a 3-D puzzle game that involves steering a ball through a hovering maze of paths and rails with obstacles such as seesaws, suspension bridges, and pendulums.

Plasticity and learning in the human mirror neuron system

I pass on a review by Welberg of an interesting study by Catmur et al. [Catmur, C., Walsh, V. & Heyes, C. Sensorimotor learning configures the human mirror system. Curr. Biol. 17, 1527–1531 (2007)]:

Neurons in the frontoparietal mirror system fire when one performs an action and when one observes someone else performing that same action. This system is thought to have a role in social cognition and, perhaps, in language acquisition. How the mirror neurons map sensory input onto its motor representation is unknown, but Catmur et al. demonstrate that these representations are not innate and can be altered by training.

The authors used transcranial magnetic stimulation (TMS) to stimulate the motor cortex of volunteers who were watching a video of a hand. When the volunteers watched the hand's index finger move, the TMS-induced motor-evoked potential (MEP) was greater in the abductor muscle of their own index finger than when they watched the little finger move; conversely, the MEP of their little finger's abductor muscle was greatest when they watched the little finger move. In other words, a muscle showed MEP enhancement when its owner watched a movement that is normally performed by that muscle; this 'mirror effect' is thought to reflect activity of the mirror neuron system.

Half of the volunteers then underwent incongruent training trials, in which they were asked to extend their little finger if the video showed a hand extending the index finger, and vice versa. People in congruent trials simply had to repeat the movement they saw in the video. The incongruent trials were assumed to train the mirror system to associate an observed finger movement with movement of a different finger of the volunteer's own hand.

Measuring TMS-induced MEPs after training, the authors found that volunteers who had undergone the incongruent training now showed greater MEPs in the muscle of one finger when watching the 'wrong' finger move in the video, indicating that a reversal of muscle-specific MEP enhancement during action observation had taken place.

This study shows that the 'mirror properties' of the mirror system are not innate. Rather, they can be trained, through sensorimotor experience, to transform observation into action. These findings imply that insufficient social interaction and consequent inadequate sensory experience might affect the development of the mirror neuron system, for example, in children with autism.

New research on ageing

Nature Magazine offers a special open access supplement with several excellent articles on recent research on ageing. Also, they offer to send a free print copy.

Striking Images....

Here are the first place winners of Science Magazine's 2007 Visualization Challenge, in which editors evaluate submissions that try to bring scientific data to life through images, illustrations, computer graphics, and animations. In the first, 182 thin CT "slices" are stacked together to create a 3D image looking upward at the sinuses from underneath the head. In the second, Irish ocean moss is spread out for photography.

How Meaning Shapes Seeing

This is the title of an interesting article by Koivisto and Revonsuo in Psychological Science. They show that semantic meaning influences inattentional blindness. Here is their abstract:

Inattentional blindness refers to the failure to see an unexpected object that one may be looking at directly when one's attention is elsewhere. We studied whether a stimulus whose meaning is relevant to the attentional goals of the observer will capture attention and escape inattentional blindness. The results showed that an unexpected stimulus belonging to the attended semantic category but not sharing physical features with the attended stimuli was detected more often than a semantically unrelated stimulus. This effect was larger when the unexpected stimuli were words than when they were pictures. The results imply that the semantic relation between the observer's attentional set and the unexpected stimulus plays a crucial role in inattentional blindness: An unexpected stimulus semantically related to the observer's current interests is likely to be seen, whereas unrelated unexpected stimuli are unseen. Attentional selection may thus be driven by purely semantic features: Meaning may determine whether or not one sees a stimulus.

Different cognitive processes underlying human mate choices and mate preferences

Starting with the assumption that the underlying function of mate choice is reproductive success, evolutionary psychologists have proposed that men should seek young, fertile, faithful women, and women should seek high-status, resourceful, committed men. This evolutionary reasoning predicts what traits people will actually tend to choose, but not necessarily what people say they will (or would like to) choose. Todd et al. suggest that different cognitive processes underlie mate preferences and actual human mate choices. Here is their abstract:

Based on undergraduates' self-reports of mate preferences for various traits and self-perceptions of their own levels on those traits, Buston and Emlen [Buston PM, Emlen ST (2003) Proc Natl Acad Sci USA 100:8805–8810] concluded that modern human mate choices do not reflect predictions of tradeoffs from evolutionary theory but instead follow a "likes-attract" pattern, where people choose mates who match their self-perceptions. However, reported preferences need not correspond to actual mate choices, which are more relevant from an evolutionary perspective. In a study of 46 adults participating in a speed-dating event, we were largely able to replicate Buston and Emlen's self-report results in a pre-event questionnaire, but we found that the stated preferences did not predict actual choices made during the speed-dates. Instead, men chose women based on their physical attractiveness, whereas women, who were generally much more discriminating than men, chose men whose overall desirability as a mate matched the women's self-perceived physical attractiveness. Unlike the cognitive processes that Buston and Emlen inferred from self-reports, this pattern of results from actual mate choices is very much in line with the evolutionary predictions of parental investment theory.

Cortical evolution and skilled hand use.

Unlike other New World species, such as squirrel monkeys, that exclusively use a power grip, cebus monkeys frequently use a precision grip in which the thumb and forefinger are brought into contact with one another to manipulate small objects, or engage in goal-directed tool use. Such a precision grip is observed in many old world monkey species, such as the macaques. Padberg et al. find:

..Unlike other New World Monkeys, but much like the macaque monkey, cebus monkeys possess a proprioceptive cortical area 2 and a well developed area 5, which is associated with motor planning and the generation of internal body coordinates necessary for visually guided reaching, grasping, and manipulation.

This is an example of parallel evolution:

...The similarity of these fields in cebus monkeys and distantly related macaque monkeys with similar manual abilities indicates that the range of cortical organizations that can emerge in primates is constrained, and those that emerge are the result of highly conserved developmental mechanisms that shape the boundaries and topographic organizations of cortical areas.

Left, Primate cladogram showing which primate taxa have the following characteristics related to manual control: complex manipulation (e.g., grasping food with one hand and peeling it with the other), use of feeding tools, corticospinal (CS) terminals in ventral horn (VH), opposable (or laterally opposable) thumb, and presence of parietal area 2. Filled box, Characteristic is present. Unfilled box: characteristic has been sufficiently tested and is absent. Right, Parietal areas and representative grasp postures traced from photographs in five primate species.
[Note: pink and green indicate areas 2 and 5 mentioned above.)

Stairways to the Mind

Alwyn Scott passed away recently. "Stairways to the Mind" was one of his books, on levels of organization and emergent properties. I knew him when he was at Wisconsin, and later read a copy of this book in draft form, to offer comments. In looking back over his work, I came across a review of the book written by Willis Harman, one of the founders of the Noetic Sciences Institute, which included a mild criticism that I don't completely agree with, but thought interesting:

Having gone so far in urging the usefulness of a hierarchical structuring of science, and having recognized (with Roger Sperry) that the consciousness level can be causal with regard to the biological or physical level (as well as the reverse), it seems a pity not to have gone one step further to recognize that the new disciplines of transpersonal psychology and anthropology, and the deepest insights of artists and mystics, can fit quite comfortably within the top level of the hierarchy. The metaphysical insight that the material world evolves within consciousness can live side by side with the complementary metaphor of consciousness as emergent from the physical.

Self-Referential Cognition in Autism

Individuals with autism spectrum conditions (ASC) have profound impairments in the interpersonal social domain, but it is unclear if individuals with ASC also have impairments in the intrapersonal self-referential domain. Lombardo et. al. give an interesting introductory discussion of the "absent self" model of Frith. They then evaluate performance of 30 subjects and:

"conclude that individuals with ASC have broad impairments in both self-referential cognition and empathy. These two domains are also intrinsically linked and support predictions made by simulation theory. Our results also highlight a specific dysfunction in ASC within cortical midlines structures of the brain such as the medial prefrontal cortex."

Figure:. Image showing the overlap in peaks of activation from studies of self-referential cognition, other-referential cognition, and theory of mind within the medial prefrontal cortex and posterior cingulate/precuneus.

Boundaries are 16mm from within midline. All peaks are taken from exemplary studies in the literature. Brain is depicted on a representative sagittal slice of the Montreal Neurological Institute (MNI) template

Brain correlates of different spatial learning strategies

Each of us tends to emphasize one of two main strategies for spacial navigation. Learning the relationships between environmental landmarks using a "spatial memory strategy" to construct a cognitive map depends on the hippocampus. Navigating using a "response strategy", or series of turns at precise decision points (turn left at corner, then turn right at...), involves the caudate nucleus and proceeds without using landmark relationships. Bohbot et al. have used a virtual maze task to examine 50 young healthy subjects, half reporting the use each strategy. Those using the spatial strategy

...had significantly more gray matter in the hippocampus and less gray matter in the caudate nucleus compared with response learners. Furthermore, the gray matter in the hippocampus was negatively correlated to the gray matter in the caudate nucleus, suggesting a competitive interaction between these two brain areas.

In a second analysis:

.. the gray matter of regions known to be anatomically connected to the hippocampus, such as the amygdala, parahippocampal, perirhinal, entorhinal and orbitofrontal cortices were shown to covary with gray matter in the hippocampus. Because low gray matter in the hippocampus is a risk factor for Alzheimer's disease, these results have important implications for intervention programs that aim at functional recovery in these brain areas. In addition, these data suggest that spatial strategies may provide protective effects against degeneration of the hippocampus that occurs with normal aging.

Ape language slips reveal category knowledge storage.

Michael Erard summarizes efforts (PDF here) to analyze 'language' errors of apes for insight into the covert mental processes of animals - analogous to such work done on human language errors He focuses on the work of Lyn, who was the first to apply the study of errors to bonobos . Kanzi and a female bonobo, Panbanisha, who now live at the Great Ape Trust in Des Moines, Iowa, can comprehend instructions and descriptions in spoken English, and they can respond by using 384 lexigrams, which they touch on a keyboard.

Lyn found that Kanzi and Panbanisha have arranged hundreds of lexigrams in their minds in a complex, hierarchical manner based mainly on their meaning. She coded the relations between all 1497 sample-error pairs along seven dimensions, including whether the lexigrams looked alike, had English words that sounded alike, or referred to objects in the same category. She found that the errors were not random but patterned. If the lexigram stood for "blackberry," the error was more likely than chance to sound like blackberry, be edible, be a fruit, or be physically similar. Errors were also more likely to be associated with more than one category. For example, "cherries" are both edibles and fruits, and the word sounds like the correct one, "blackberries." All this indicated to Lyn that mental representations of the lexigrams must be stored not as simple one-to-one associations but in more complex arrangements. This suggests that, given the chance, bonobos and other apes can acquire systems of meaning that are closer than anyone has thought to what humans do, and that some aspects of language acquisition are not unique to humans.

Symbiosis of human brains and the web...

George Johnson notes that the web has stripped the word algorithm (a recipe for solving problems step by step) of its innocence. The algorithms used by Google search, Amazon, MySpace, etc. perform an intelligence amplification, leveraging human thinking with machines in the service of selling more goods. The boundary between human and computer responses increasingly blurs. Submit or change a Wikipedia article and "a swarm of warm- and sometimes hot-blooded proofreading routines go to work making corrections and corrections to the corrections." Here is the PDF of Johnson's article.

Moral Universals

Nicholas Wade offers a summary (PDF here) of some of the evidence that humans have an evolved moral intuition that appeared before the development of language. (This has been the subject of several previous blog posts), focusing on the views of Jonathan Haidt. Haidt suggests that there are five innate moral systems, or rather, innate psychological mechanisms that predispose children to absorb certain virtues. Some concern the protection of individuals, others the ties that bind a group together. Of the moral systems that protect individuals, one is concerned with preventing harm to the person and the other with reciprocity and fairness. Less familiar are the three systems that promote behaviors developed for strengthening the group. These are loyalty to the in-group, respect for authority and hierarchy, and a sense of purity or sanctity.

A striking demonstration comes from experiments that show that people will say it is morally acceptable to pull a switch that diverts a train, killing just one person instead of the five on the other track. But if asked to save the same five lives by throwing a person in the train’s path, people will say the action is wrong. This may be evidence for an ancient subconscious morality that deters causing direct physical harm to someone else. An equally strong moral sanction has not yet evolved for harming someone indirectly.

Emotion and Disorders of Emotion

You might want to check out this open access special focus issue of Nature Magazine on emotion and disorders of emotion. The starting editorial introduces the articles. Individual susceptibility to depression and anxiety in response to life stressors may be related to genetic variation, and I would point to the review article by Klaus-Peter Lesch and Turhan Canli. It explores how individual variation in the serotonin transporter gene may interact with personality, emotion regulation and social cognition.