Multigenerational Impacts of Childhood Access to the Safety Net.

In an open source article in the January issue of the American Economic Review East et al. show that early life exposure to Medicaid enhances the next generation's health.

We examine multigenerational impacts of positive in utero health interventions using a new research design that exploits sharp increases in prenatal Medicaid eligibility that occurred in some states. Our analyses are based on US Vital Statistics natality files, which enables linkages between individuals' early life Medicaid exposure and the next generation's health at birth. We find evidence that the health benefits associated with treated generations' early life program exposure extend to later offspring. Our results suggest that the returns on early life health investments may be substantively underestimated.

Shifting from foraging to farming, beginning ~12,000 years ago, changed everything.

A special Feature section in the Jan. 17 issue of PNAS offers a series of perspectives on the past 12,000 years of human behavior, adaptation, and evolution that shaped who we are today. An introduction to the special section by Larsen does an overview and brief summary of each of perspectives presented. I pass on the last paragraph (Conclusions) of that summary:

In evolutionary terms, the transition at the Pleistocene–Holocene boundary was extraordinary, especially in consideration of the beginning of a fundamental shift in dietary focus and the downstream effects of diets based on domesticated plants and animals. The transition provided the context for a remarkable increase in population. However, the costs for that success—elevated levels infectious diseases, undernutrition, and conflict—are still with us today. Our species will continue to adapt, to develop strategies for success, and to mitigate challenges. That is what we do. Once we began the shift to and intensification of farming, the remarkable changes seen in humans became critically important developments in recent human evolution. In view of conditions today, including climate change, overpopulation, and the rise in prevalence of infectious diseases, both old and newly emerging, it should come as no surprise that dependence on a few staple crops and shift to sedentary behavior will be with us for the foreseeable future. They are, after all, a legacy of our past, and forming and sharing of the dietary framework, behavioral patterns, and outcomes in health and well-being for all eight billion of us that occupy the world today.

Openness to spiritual experiences...with caution

After a Protestant Christian upbringing (I was a teenage organist in an Austin Lutheran Church, and took a course from theologian Paul Tillich at Harvard), my adult materialistic scientific Deric has never been able to fathom how an intellectual like Ross Douthat could be a devout Catholic. My irrational faith is in a materialism that is open to spiritual experiences and insights, but also strives to explain them in materialistic terms (as I think near-death experiences have been). I think Douthat’s recent opinion piece in the NYTimes very lucid, although I take exception to one of his pronouncements, and I would recommend that you read it. Here are some clips:

...the dissolution of the old order of American religion — the decline of churches and denominations and the rise of deinstitutionalized spirituality — means that more and more religious lives are lived in between worldviews, in experimental territory where it’s a mistake to expect coherence, theological consistency, a definite set of prior assumptions or beliefs...I want to defend the rationality of this kind of spiritual experimentation and then to warn about its dangers.

Douthat then offers three examples experimental style: magical thinking, experimenting with psychedelics, and pantheistic art that blurs spiritual traditions. And he continues:

For the stringent materialist, everything I’ve just described is reasonable as long as it's understood to be playacting, experience hunting, artistic experimentation. Only when it becomes serious does it offend against rationality.

However, stringent materialism is itself a weird late-modern superstition, and the kind of experimentation I’m describing is actually far more rational than a life lived as though the universe is random and indifferent and human beings are gene-transmission machines with an illusion of self-consciousness.

So... put me in the camp of irrational believers in stringent materialism. And... by what authority does Mr. Douthat get to declare spiritual experimentation or superstition is "far more rational than life lived as though the universe is random, etc." Superstition is superstition; irrational is irrational. What criteria are Mr. Douthat using for his "far more rational" judgment. Are they utilitarian?... as in "X diminishes or enhances the well being of humans more than Y"? He should explicitly state them.

Cryptocurrency isn't going away - any more that Gold is...

...as long as cryptocurrency maintains a core of true believers in the block chain concept for guaranteeing trustworthiness. All currencies are useful as tokens for exchange only to the extent that humans believe in them. The point of this brief post is just to pass on links to two recent screeds by Desai and Krugman that make entertaining reading: 

Mihir A. Desai - The Crypto Collapse and the End of the Magical Thinking That Infected Capitalism  

Paul Krugman - Wonking Out: Give Me That Gold Time Religion 

 

 

 

Market exposure and human morality

In the face of resurgent threats to place religion over the rest of civil society, and specious claims that we can't have a moral society without the (varying) moral injunctions of various religions, this recent article by Enke in Nature Human Behavior offers a nice explication of one of several other routes by which moral behaviors have evolved over time. Here is the abstract:

According to evolutionary theories, markets may foster an internalized and universalist prosociality because it supports market-based cooperation. This paper uses the cultural folklore of 943 pre-industrial ethnolinguistic groups to show that a society’s degree of market interactions, proxied by the presence of intercommunity trade and money, is associated with the cultural salience of (1) prosocial behaviour, (2) interpersonal trust, (3) universalist moral values and (4) moral emotions of guilt, shame and anger. To provide tentative evidence that a part of this correlation reflects a causal effect of market interactions, the analysis leverages both fine-grained geographic variation across neighbouring historical societies and plausibly exogenous variation in the presence of markets that arises through proximity to historical trade routes or the local degree of ecological diversity. The results suggest that the coevolutionary process involving markets and morality partly consists of economic markets shaping a moral system of a universalist and internalized prosociality.

How sleep shapes what we remember and forget.

I have found monitoring the quality of my sleep to be a fascinating and useful activity. I use both the Oura ring and Apple watch to monitor body temperature, body movement, heart rate, and heart rate variability, and then compare their different (but broadly similar) algorithmic estimates of deep sleep, REM sleep, non-REM sleep, and wake periods. I'm on the lookout for articles on sleep during my scans of journals' tables of contents, and have come upon this review by Sakai of what is happening in our sleep to be concise and useful. Below is a more general overview from edited and rearranged clips (The article goes into more electrophysiological and cellular details):

 

(image credit Dave Cutler)

...memory at the beginning of the consolidation process is very much anchored in hippocampal networks, and in the end of this process, it primarily resides in neocortical networks...New memories are rich with contextual clues such as the time, place, and sensory details of an experience...as memories get encoded in the cortex, many of those spatial and temporal details fade...forgetting—through weakening or loss of synapses—seems to play a key role in the process of memory consolidation, especially during sleep... What remains are the elements representing the essential core of the memory. When learning how to drive, for example, the movements needed to steer and brake are critical; the details of avoiding a specific car on a particular outing are not...sleep’s role in memory is not simply about passive storage. Rather..a more active process of consolidation that extracts key information and forms a generalized version of the overall memory that can later be accessed and applied to relevant situations.

Sleep in mammals has distinct phases as characterized by specific EEG patterns. These include brain-wide slow oscillations (less than 1 Hz in frequency), sharp-wave ripples (100-300 Hz) in the hippocampus, and spindles (10-15 Hz), which are related to the firing of neurons in the circuits connecting the thalamus and the cortex. Upon onset of sleep, the brain enters a non-rapid eye movement (non-REM) phase. During non-REM sleep, slow oscillations sweep across large regions of the brain, punctuated by swells of spindles and bursts of sharp wave-ripples. A period of rapid eye movement (REM) sleep follows, with characteristic bursts of its namesake eye movements and low-amplitude theta oscillations around 4-8 Hz. The brain cycles through these phases throughout the sleep period, with slow-wave, non-REM sleep dominating the early hours and REM sleep the late hours.

There are...

...distinct roles of different stages of sleep in memory formation. Non-REM sleep has been shown to be very important for consolidation of declarative memories—those based on recall of information—while REM sleep seems to play a larger part in procedural or task-based memories...this may relate to the degree of synaptic change required. For declarative memories, most of the foundational learning has already taken place; remembering a new fact likely requires only small changes in synaptic strengths. By contrast, procedural memories require a massive amount of synaptic change...If you want to learn how to ride a bike, or how to play capoeira … it's not like learning a new name...I’s weeks, months, years of work. And so it seems like REM sleep is really, really necessary to do this long-term persistent synaptic change.”

MindBlog's 2010 recital and lecture in Istanbul

I've been meandering back over old MindBlog posts and found an orphaned .mov file that I've reposted to my YouTube channel, quite a bit of nostalgia. The guy turning my pages was my handler and guide during my 10 day visit to Istanbul. He is now a Turkish Airlines pilot. 

 

The Evolution of Peace

I pass on the abstract of an article by Luke Glowacki that has been submitted to the network of Behavioral and Brain Science reviewers who might offer commentary on its arguments. Motivated readers can obtain a copy of the article from me.

Abstract: While some species have affiliative and even cooperative interactions between individuals of different social groups, humans are alone in having durable, positive-sum, interdependent relationships across unrelated social groups. Our capacity to have harmonious relationships that cross group boundaries is an important aspect of our species' success, allowing for the exchange of ideas, materials, and ultimately enabling cumulative cultural evolution. Knowledge about the conditions required for peaceful intergroup relationships is critical for understanding the success of our species and building a more peaceful world. How do humans create harmonious relationships across group boundaries and when did this capacity emerge in the human lineage? Answering these questions involves considering the costs and benefits of intergroup cooperation and aggression, for oneself, one's group, and one's neighbor. Taking a game theoretical perspective provides new insights into the difficulties of removing the threat of war and reveals an ironic logic to peace—the factors that enable peace also facilitate the increased scale and destructiveness of conflict. In what follows, I explore the conditions required for peace, why they are so difficult to achieve, and when we expect peace to have emerged in the human lineage. I argue that intergroup cooperation was an important component of human relationships and a selective force in our species history in the past 300 thousand years. But the preconditions for peace only emerged in the past 100 thousand years and likely coexisted with intermittent intergroup violence which would have also been an important and selective force in our species' history.

Our different styles of thinking.

An interesting recent article by Joshua Rothman, the ideas editor of newyorker.com, notes several recent books that describe different styles of thinking. A few clips:

In “Visual Thinking: The Hidden Gifts of People Who Think in Pictures, Patterns, and Abstractions,” Temple Grandin identifies a continuum of thought styles that’s roughly divisible into three sections. On one end are verbal thinkers, who often solve problems by talking about them in their heads or, more generally, by proceeding in the linear, representational fashion typical of language. (Estimating the cost of a building project, a verbal thinker might price out all the components, then sum them using a spreadsheet—an ordered, symbol-based approach.) On the other end of the continuum are “object visualizers”: they come to conclusions through the use of concrete, photograph-like mental images, as Grandin does when she compares building plans in her mind. In between those poles, Grandin writes, is a second group of visual thinkers—“spatial visualizers,” who seem to combine language and image, thinking in terms of visual patterns and abstractions.

Grandin proposes imagining a church steeple. Verbal people, she finds, often make a hash of this task, conjuring something like “two vague lines in an inverted V,” almost as though they’ve never seen a steeple before. Object visualizers, by contrast, describe specific steeples that they’ve observed on actual churches: they “might as well be staring at a photograph or photorealistic drawing” in their minds. Meanwhile, the spatial visualizers picture a kind of perfect but abstract steeple—“a generic New England-style steeple, an image they piece together from churches they’ve seen.” They have noticed patterns among church steeples, and they imagine the pattern, rather than any particular instance of it.

The imagistic minds in “Visual Thinking” can seem glamorous compared with the verbal ones depicted in “Chatter: The Voice in Our Head, Why It Matters, and How to Harness It,” by Ethan Kross. Kross is interested in what’s known as the phonological loop—a neural system, consisting of an “inner ear” and an “inner voice,” that serves as a “clearinghouse for everything related to words that occurs around us in the present.” If Grandin’s visual thinkers are attending Cirque du Soleil, then Kross’s verbal thinkers are stuck at an Off Broadway one-man show. It’s just one long monologue.

People with inner monologues, Kross reports, often spend “a considerable amount of time thinking about themselves, their minds gravitating toward their own experiences, emotions, desires, and needs.” This self-centeredness can spill over into our out-loud conversation. In the nineteen-eighties, the psychologist Bernard Rimé investigated what we’d now call venting—the compulsive sharing of negative thoughts with other people. Rimé found that bad experiences can inspire not only interior rumination but the urge to broadcast it. The more we share our unhappiness with others, the more we alienate them… Maybe it can pay to keep your thoughts to yourself.

Kross’s bottom line is that our inner voices are powerful tools that must be tamed. He ends his book with several dozen techniques for controlling our chatter. He advises trying “distanced self-talk”: by using “your name and the second-person ‘you’ to refer to yourself,” he writes, you can gain more command over your thinking. You might use your inner voice to pretend that you’re advising a friend about his problems; you might redirect your thoughts toward how universal your experiences are (It’s normal to feel this way), or contemplate how every new experience is a challenge you can overcome (I have to learn to trust my partner). The idea is to manage the voice that you use for self-management. Take advantage of the suppleness of dialogue. Don’t just rehearse the same old scripts; send some notes to the writers’ room.

If we can’t say exactly how we think, then how well do we know ourselves? In an essay titled “The Self as a Center of Narrative Gravity,” the philosopher Daniel Dennett argued that a layer of fiction is woven into what it is to be human. In a sense, fiction is flawed: it’s not true. But, when we open a novel, we don’t hurl it to the ground in disgust, declaring that it’s all made-up nonsense; we understand that being made up is actually the point. Fiction, Dennett writes, has a deliberately “indeterminate” status: it’s true, but only on its own terms. The same goes for our minds. We have all sorts of inner experiences, and we live through and describe them in different ways—telling one another about our dreams, recalling our thoughts, and so on. Are our descriptions and experiences true or fictionalized? Does it matter? It’s all part of the story.

A quick MindBlog riff on what a self is....

Spilling out what I was thinking at breakfast this morning, deciding to fire it off, probably incomprehensible to most readers, perhaps to attempt to clarify later (or delete!):

My self model or 'I' stands amongst my models of others, and during my early postnatal period I probably formed those other models prior to my own, a yet unknown self discovering and learning to predict the behavior of others to gain feeding and care, and only then composing my own self from parts of them. This is consonant with Graziano's take on consciousness as a perceptual construct ("Consciousness and the Social Brain"), also with Wegner's self as being the emotion of authorship ("The Illusion of Conscious Will") and with Metzenger's emotions as evolved virtual organs analogous to the hardware of the liver or kidney ("The Ego Tunnel"). Perhaps the closest we come to a 'real fundamental self' is the experience of occupancy of an expanded space (of non-dual consciousness) that feels to be the container for all of this.

Mindful attention enhances brain network control and uncouples past from the present

Zhou et al. (open source) do an interesting experiment on mindfulness and brain network control:  

Significance

Practicing mindfulness helps individuals regulate attention, thoughts, feelings, and behavior. In recognizing these benefits, various schools, workplaces, and clinics are increasingly teaching mindfulness. How does mindful attention change brain function to support self-regulation? Addressing this question could inform how we teach mindfulness and whom we expect to benefit. We modeled the defining components of mindful experience using tools that probe the structure and function of the brain’s network. In a randomized controlled study of alcohol consumption, we found that a brain network’s dynamic shape predicts individuals’ future alcohol consumption and explains otherwise elusive components of mindful experience, such as being present. Our results provide new understanding of how mindful attention affects brain function.

Abstract

Mindful attention is characterized by acknowledging the present experience as a transient mental event. Early stages of mindfulness practice may require greater neural effort for later efficiency. Early effort may self-regulate behavior and focalize the present, but this understanding lacks a computational explanation. Here we used network control theory as a model of how external control inputs—operationalizing effort—distribute changes in neural activity evoked during mindful attention across the white matter network. We hypothesized that individuals with greater network controllability, thereby efficiently distributing control inputs, effectively self-regulate behavior. We further hypothesized that brain regions that utilize greater control input exhibit shorter intrinsic timescales of neural activity. Shorter timescales characterize quickly discontinuing past processing to focalize the present. We tested these hypotheses in a randomized controlled study that primed participants to either mindfully respond or naturally react to alcohol cues during fMRI and administered text reminders and measurements of alcohol consumption during 4 wk postscan. We found that participants with greater network controllability moderated alcohol consumption. Mindful regulation of alcohol cues, compared to one’s own natural reactions, reduced craving, but craving did not differ from the baseline group. Mindful regulation of alcohol cues, compared to the natural reactions of the baseline group, involved more-effortful control of neural dynamics across cognitive control and attention subnetworks. This effort persisted in the natural reactions of the mindful group compared to the baseline group. More-effortful neural states had shorter timescales than less effortful states, offering an explanation for how mindful attention promotes being present.

COVID-19 and brain aging

Over the Christmas and New Year's holidays I was hit first by a mild Covid infection that lasted only a few days (I've had all 5 vaccinations and immediately took Paxlovid on testing positive) and then five days later had a slightly longer Paxlovid-rebound infection. A transient brain fog seems to have cleared by now. This personal experience makes me especially attentive to articles like Welberg's note on Covid-19 and brain aging, which suggests that brain changes associated with Covid infection are most likely due to neuroinflammation resulting from the infection, not from the virus itself. Here is the abstract:

Severe COVID-19 has been associated with cognitive impairment and changes in the frontal cortex. In a study published in Nature Aging, Mavrikaki, Lee et al. performed RNA sequencing on frontal cortex samples from 21 individuals with severe COVID-19, 22 age- and sex-matched uninfected controls, and 9 uninfected people who had received intensive care or ventilator treatment. The authors found almost 7,000 differentially expressed genes (DEGs) in the patient samples compared to controls. Upregulated DEGs were enriched for genes involved in immune-related pathways, and downregulated DEGs were enriched for genes involved in synaptic activity, cognition and memory — a profile of transcriptional changes that resembles those previously observed in aging brains. Direct comparisons between frontal cortex samples from young and old individuals confirmed this overlap. Application of tumor necrosis factor, interferon-β or interferon-γ to cultured human primary neurons induced transcriptional changes similar to those seen in patients with severe COVID-19. As no SARS-CoV-2 RNA was detected in the patient samples, these data suggest that the transcriptomic changes in frontal cortex of patients with severe COVID-19 were due to neuroinflammatory processes rather than a direct effect of the virus.

Materialism meets transcendence

I want to pass on the URL to a PBS series by Alan Lightman that I plan to start watching as soon as I can, based on the following description and review in Science Magazine:

In part 1, “The Stars & The Osprey,” Lightman undergoes functional magnetic resonance imaging and interviews neuroscientist Robert Desimone about how much neuroimaging can tell us about Lightman’s transcendental experience. He ultimately finds this approach unsatisfying and introduces viewers to the debate between mechanists, who believe that the laws of physics, chemistry, and biology are sufficient to explain life, and vitalists, who believe that living creatures are imbued with an additional spiritual quality not explainable by science.

Here, he interviews biologist and Nobel laureate Jack Szostak and the Dalai Lama as proponents of these two camps, respectively. Although the Dalai Lama expresses enthusiasm for scientific investigation, most scientists will likely resonate with Szostak’s declaration that “It’s not just atoms and molecules, it’s the organization…it’s no less wonderful or beautiful because we understand that there is a natural origin for [life].”

Part 2, “The Big & The Small,” begins with the familiar “powers of 10” view of the Universe, moving from the subatomic to the galactic. Lightman then queries what such explorations have to do with consciousness, conversing with BINA48, an extraordinary humanoid robot programmed by artificial intelligence with >100 hours of a real woman’s memories. Here, he speculates that BINAs of the future may achieve consciousness. He then probes this issue over Zoom with the Dalai Lama, whom viewers observe watching a movie of BINA48 conversing with the woman from whom BINA48 was programmed; this multilayered interaction is simultaneously disconcerting, comical, and wondrous. After additional interviews with a bioethicist, a rabbi, and others, Lightman ultimately concludes that we may be just atoms and molecules, but, in the words of Emily Dickinson, “The brain is wider than the sky.”

In part 3, “Homo Techno,” Lightman contemplates our inner world of perception, consciousness, and self-awareness. He meets Erik Sorto, who lost all movement from the neck down after being shot in the back. With electrodes implanted into his posterior parietal cortex and 2 years of training, Sorto learned to control the movement of a robotic arm by thought. This is an extraordinary achievement, and Lightman posits that it is an example of the beginning of our transition from Homo sapiens into Homo techno, part-human, part-machine entities that reflect the modification of human evolution by technological means. From an actual evolutionary biology standpoint, this is nonsensical, and it is unclear that Lightman even means to propose such an idea, but this section’s loose language will rankle some viewers.

At another point in the series’ final episode, Lightman finds himself dizzy from talk of neurons and galaxies and takes refuge in closely examining a single square inch of earth. His biophilia is obviously meaningful to him, and it would have been stimulating had the episode included interviews with an evolutionary biologist or naturalist, who might have helped to better articulate this facet of the human experience. The series closes, appropriately, with philosophical musings about the need for each of us to find meaning for ourselves.

A small problem at the outset is the inherent impossibility of conveying transcendence through description—the degree to which viewers relate to Lightman’s moment of enlightenment will depend on their own experiences and inclinations. Additionally, Lightman’s screen persona leaves something to be desired. There are, however, few people better qualified to explore these issues, and as the series progresses, his humanity shines through, bringing a welcome lightness to some potentially ponderous material.

Despite its focus on phenomena currently unexplainable by science, Searching is full of the joy and passion that can be found in the doing of science and succeeds in conveying how deeply meaningful science is to its practitioners. It is well worth your time and is especially recommended to families with kids curious about life and our world.

Awe as a Pathway to Mental and Physical Health

Reading this open source review from Maria Monroy and Dacher Keltner leaves me feeling substantially more mellow! Their abstract, followed by a quote from Emerson, and then a summary graphic...

How do experiences in nature or in spiritual contemplation or in being moved by music or with psychedelics promote mental and physical health? Our proposal in this article is awe. To make this argument, we first review recent advances in the scientific study of awe, an emotion often considered ineffable and beyond measurement. Awe engages five processes—shifts in neurophysiology, a diminished focus on the self, increased prosocial relationality, greater social integration, and a heightened sense of meaning—that benefit well-being. We then apply this model to illuminate how experiences of awe that arise in nature, spirituality, music, collective movement, and psychedelics strengthen the mind and body.

and,

In the woods, we return to reason and faith. There I feel that nothing can befall me in life—no disgrace, no calamity (leaving me my eyes), which nature cannot repair. Standing on the bare ground—my head bathed by the blithe air and uplifted into infinite space—all mean egotism vanishes. I become a transparent eyeball; I am nothing; I see all; the currents of the Universal Being circulate through me; I am part or parcel of God. The name of the nearest friend sounds then foreign and accidental; to be brothers, to be acquaintances, master or servant, is then a trifle and a disturbance. I am the lover of uncontained and immortal beauty.

-from Emerson R. W. (1836). Nature. Reprinted in Ralph Waldo Emerson, Nature and Other Essays (2009). Dover.

Fig. 1. Model for awe as a pathway to mental and physical health. This model shows that awe experiences will lead to the mediators that will lead to better mental and physical-health outcomes. Note that the relationships between awe experiences and mediators, and mediators and outcomes have been empirically identified; the entire pathways have only recently begun to be tested. One-headed arrows suggest directional relationships, and two-headed arrows suggest bidirectionality. DMN = default-mode network; PTSD = posttraumatic stress disorder.

AI After Death: interactions with AI representations of the deceased

 I want to pass on to MindBlog readers the following excellent notes that Terry Allard made to guide a discussion at the Nov. 29, 2022 session of the Chaos & Complex Systems Discussion group at the Univ. of Wisconsin. 

Chaos & Complex Systems Discussion

AI After Death: interactions with AI representations of the deceased
November 29, 2022
Source material: Washington Post; Nov 12, 2022, by Caren Chesler: AI’s New Frontier https://www.washingtonpost.com/health/2022/11/12/artificial-intelligence-grief/ See also https://www.media.mit.edu/projects/augmented-eternity/overview/

AI companies have begun mining digital content and real world interview to create AI representations of people with whom their survivors can interact.

The digital representations are created from social media posts, email, electronic surveillance, voice recordings and sometimes actual interviews with the targets before they pass away.

The interaction can be made directly with visual, audio or text avatars.

• The documentary, “Meeting You,” created a digitized re-creation of a recently lost child that the mother could see through a virtual reality headset.

• Augmented Eternities (MIT Media Lab) This project uses a distributed machine intelligence network to enable its users to control their growing digital footprint, turn it into their digital representation, and share it as a part of a social network.

  Our digital identity has become so rich and intrinsic that without it, it may feel like a part of us is missing. The number of sensors we carry daily and the digital footprints we leave behind have given us enough granular patterns and data clusters that we can now use them for prediction and reasoning on behalf of an individual. We believe that by enabling our digital identity to perpetuate, we can significantly contribute to global expertise and enable a new form of an intergenerational collective intelligence.

  https://www.media.mit.edu/projects/augmented-eternity/overview/

• Amazon unveiled a new feature it’s developing for Alexa, in which the virtual assistant can read aloud stories in a deceased loved one’s voice

• Several entrepreneurs in the AI sphere, including James Vlahos of HereAfter AI and Eugenia Kuyda, who co-founded AI start-ups Luka and Replika, have turned their efforts toward virtual representations of people, using data from their digital footprint to craft an avatar or chatbot that can interact with family members after they’ve passed.

  HereAfter’s app takes users through an interview process before they’ve died, prompting them to recollect stories and memories that are then recorded. After they’ve passed, family members can ask questions, and the app responds in the deceased’s voice using the accumulated interview information, almost like it’s engaging in a conversation.

  Some Questions for Discussion:

1. How does posthumous interaction benefit the survivors? Are there risks? Could it lead to someone wanting to remain in this virtual world of their loved one?

2. Could posthumous digital avatars have a therapeutic benefit for the grieving?

3. Can digital avatars replace human interaction writ large?

4. Can digital avatars learn and evolve on their own?

5. Are digital avatars alive or could they be? How do we define sentience?

6. Will “deep fakes” compromise trust in online person-to-person interactions?

7. Can people download their identities into digital form and transcend (cheat) death?

 

Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertainty

Wow, in an article with title of this post Breznau et al. show that different research teams presented independently with the same data and social science hypothesis reach opposing conclusions about what the data show.  

Significance

Will different researchers converge on similar findings when analyzing the same data? Seventy-three independent research teams used identical cross-country survey data to test a prominent social science hypothesis: that more immigration will reduce public support for government provision of social policies. Instead of convergence, teams’ results varied greatly, ranging from large negative to large positive effects of immigration on social policy support. The choices made by the research teams in designing their statistical tests explain very little of this variation; a hidden universe of uncertainty remains. Considering this variation, scientists, especially those working with the complexities of human societies and behavior, should exercise humility and strive to better account for the uncertainty in their work.

Abstract

This study explores how researchers’ analytical choices affect the reliability of scientific findings. Most discussions of reliability problems in science focus on systematic biases. We broaden the lens to emphasize the idiosyncrasy of conscious and unconscious decisions that researchers make during data analysis. We coordinated 161 researchers in 73 research teams and observed their research decisions as they used the same data to independently test the same prominent social science hypothesis: that greater immigration reduces support for social policies among the public. In this typical case of social science research, research teams reported both widely diverging numerical findings and substantive conclusions despite identical start conditions. Researchers’ expertise, prior beliefs, and expectations barely predict the wide variation in research outcomes. More than 95% of the total variance in numerical results remains unexplained even after qualitative coding of all identifiable decisions in each team’s workflow. This reveals a universe of uncertainty that remains hidden when considering a single study in isolation. The idiosyncratic nature of how researchers’ results and conclusions varied is a previously underappreciated explanation for why many scientific hypotheses remain contested. These results call for greater epistemic humility and clarity in reporting scientific findings.

A deep-learning model of prescient ideas demonstrates that they emerge from the periphery

 The abstract of a fascinating open source article from Vicinanza et al.:

Where do prescient ideas—those that initially challenge conventional assumptions but later achieve widespread acceptance—come from? Although their outcomes in the form of technical innovation are readily observed, the underlying ideas that eventually change the world are often obscured. Here we develop a novel method that uses deep learning to unearth the markers of prescient ideas from the language used by individuals and groups. Our language-based measure identifies prescient actors and documents that prevailing methods would fail to detect. Applying our model to corpora spanning the disparate worlds of politics, law, and business, we demonstrate that it reliably detects prescient ideas in each domain. Moreover, counter to many prevailing intuitions, prescient ideas emanate from each domain's periphery rather than its core. These findings suggest that the propensity to generate far-sighted ideas may be as much a property of contexts as of individuals.

Enlightenment, Habituation, and Renewal - Or, Mindfulness as the opiate of the thinking classes?

This New Year’s post is directed to the small number of MindBlog readers who might be sympathetic to some of my private random rants. Perhaps I should keep them to myself, but here goes…..

All enlightenment traditions - such as Abrahamic, Buddhist, Hindu, or other schools of meditative insight - have a common issue. How can the central canon or dogma of the way things are be renewed and kept fresh? The usual practice is to repeat a liturgy set down by gurus of a given tradition, but with each repetition by a particular vendor the gospel begins to loose its force. The transforming clarity of the initial enlightenment fades as the habituation and desensitization associated with all repetitive activities begins to set in. ‘Reset buttons’ that are temporarily effective can sometimes be found by turning to different vendors of the central message, who in this smartphone age can each package and deliver their respective theory or practice sessions in a sonorous and calming voices. This frequently is done in 10-30 min chunks that better accommodate our modern diminished attention spans, as well as in longer lectures from workshops or retreats. This approach can be seen in aggregator Apps such as Sam Harris’ “Waking Up,” which delivers the messages of many different teachers. (I wonder if generation Alpha,  born in this century, exists in even more transient states of tik-tok mind, twitter mind, or instagram mind that preclude even this level of engagement?)

I would guess that over the past year or two I have listened to ~150 such lectures. As I see the same basic points reframed in many different ways, I begin to think “Y’know, it seems that the fundamental axioms of enlightenment that are expressible in language are being repetitively rediscovered throughout history and repeatedly archived.  I feel like their verbal messages are as ingrained in my consciousness as the language of the mathematical and chemical structures I have known most of my life.”

My flippant ‘mindfulness as the opiate of the thinking classes’ phrase in the title of this post is meaning to point to the fact that the market for vendors of enlightenment is a distinctive one. Existential angst, or worrying about value, purpose, and meaning seem most pressing to a relatively small number of highly urbanized and literate humans. I can’t imagine that my two Abyssinian cats, who I sometimes takes to be my best role models, spend a significant fraction of their time worrying about the meeting of it all, or pondering the subtleties of epistemology and ontology. 

So….what beyond words? A space or perspective that doesn’t contain them can only be pointed at by using them in the dualistic context of a sender and receiver. I can, for example, try to use words to give a crude voice to the mute homeostatic generative visceral organic axes of valence and arousal that underlie and generate everything that I am and experience right now: “Dude, get a grip, I (the visceral one) am the one who is actually running this show, deciding where it goes and whether it works or shuts down, the sooner the “I” you imagine yourself to be realizes this and lets go, the sooner some kind of sane space is attained. All of the surface behaviors acted out for others to see - the family man, the professor, the pianist - are shadow play shimmering on the surface of this basic organic substrate, like water insects skittering around on the surface of a pond. What is writing these words is just another one of the contents of consciousness flitting past. Just turn yourself around to look quickly for the writer…what do you see? What do you see as you imagine being first born into this world? The brief glimpses of expanded naive awareness sometimes elicited by questions such as these have the potential of permitting a scrubbing, refreshing, or renewal of consciousness in a way that permits more choice in selecting which prior individual selves and self habits rise to compose current self conscious life. 

Different iterations of these sentiments, different vendings of the sort mentioned in the first paragraph above, can be found in two previous MindBlog posts. One from Nov. 25:  

Perhaps an increasing number of people who engage techniques for facilitating non-dual awareness find themselves seeing and experiencing the "I" or self that feels threatened by our anxious times from a more useful perspective - an inclusive expanded awareness that includes the reporting "I" or self as just one of its many contents that include passing thoughts, perceptions, actions, and feelings.  A calm can be found in this expanded awareness that permits a  dis-association of the experienced breathing visceral center of gravity of our animal body from the emotional and linguistic veneer of politics and conflict. This does not remove the necessity of facing various societal dysfunctions, but offers the prospect of doing so without debilitating the organic physiological core from which everything we experience rises.  

And the other from Oct. 26, passing on a masterful exposition from James Low that I can not improve on.

If you want stability, if you want real peace, you already have that in the nature of awareness. But if you look to manifestation, to patterning of yourself, to thinking you could establish a stable personalty, to live a life in which you were happy all the time, or in which you were your own person, that way madness lies. To find our original face, to find the ground of our primordial being, we need to release our fixation on the dialogic movement of subject and object, and allow ourselves to be the space within which the movement of experience is occurring. Awareness means being aware that we are present without being something as such. This is a great mystery. When we look at phenomena the world, things exist as something. A car is not a cow, an apple is not an orange, compare and contrast, category allocation. That’s how our cognition, our conceptual elaboration functions to give a seemingly enduring structure to identifications. But awareness can’t be caught. It’s not a thing. You can’t pin a tail on the donkey, there is no donkey there. The mind is not an object for itself, it is self luminous awareness, but you can’t catch it. You can never know your mind but you can be your mind. We are awareness and that’s a very important distinction.

The pitfalls of defining neural correlates of brain functions

Rust and Le Doux do a useful brief opinion piece from which I pass on two clips, and recommend you read the whole open source text.

...neuroscientists should avoid conflating circuits that control behavior with mental states, especially in the absence of evidence that the two map onto one another. These equivalencies need to be very carefully investigated rather than presumed.

Considerable evidence suggests that circuits involving the amygdala control behavioral and physiological responses to threats. In animal research labs, threats are often recapitulated by pairing a tone with an aversive stimulus such as a weak shock to elicit ‘fear-related behaviors’ such as freezing upon hearing the tone again. The neural circuits that learn the association between the tone and shock and produce freezing behavior are among the best understood in the brain. The problem lies in labeling these circuits with the term ‘fear’, because it presumes that the threat elicits a mental state, a subjective experience, of fear that is caused by activity in the amygdala. However, mounting evidence suggests that the amygdala is not required for the mental state of fear. Instead, the mental state of fear crucially depends, at least in part, on cortical circuits that interpret or conceptualize what is occurring in the social and physical environment and in one’s body. In this framework, amygdala circuits control nonconscious defense behaviors (such as freezing) as opposed to conscious experience. Should this framework be correct, the extensive ongoing efforts devoted to targeting amygdala circuits and rodent behaviors such as freezing and avoidance are unlikely to provide a direct route to treatments for human fear and anxiety disorders. These lines of research can help, but not without recognizing the centrality of subjective experience.

Wormholes in quanturm computers

I pass on this link to a YouTube video sent out by the Chaos and Complex Systems Discussion group at the University of Wisconsin. Totally fun to watch, but I don't think any of us understand it.

Rigorous study does not find that exercise and mindfulness training improve cognitive function in older adults.

Wow, here is a study by Lenze et al. - not confirming the results of numerous other less rigorous studies reported in MindBlog posts - that is unable to demonstrate that the use of mindfulness training, exercise, or a combination of both can significantly improving cognitive function in older adults with subjective cognitive concerns. In their randomized clinical trial that included 585 participants, mindfulness training, exercise, or both did not result in significant differences in improvement in episodic memory or executive function composite scores at 6 months. Gretchen Reynolds provides context and a summary of the work in a Washington Post article.

A smart phone intervention that enhances memory in older adults.

Martin et al.  offer an open source article that describes a smartphone intervention that enhances real-world memory and promotes differentiation of hippocampal activity in older adults.  I have downloaded the HippoCamera smartphone App described in the text from the Apple App Store, and found a research passcode is required, for which the following clip of text from the article is relevant: "As of the time of writing, this is a research-dedicated application that requires an access code that can be obtained from a corresponding author."

Significance

The ability to vividly recollect our past declines with age, a trend that negatively impacts overall well-being. We show that using smartphone technologies to record and replay brief but rich memory cues from daily life can improve older adults’ ability to reexperience the past. This enhancement was associated with corresponding changes in the way memories were stored in the brain. Functional neuroimaging showed that repeatedly replaying memory cues drove memories apart from one another in the hippocampus, a brain region with well-established links to memory function. This increase in differentiation likely facilitated behavior by strengthening memory and minimizing competition among different memories at retrieval. This work reveals an easy-to-use intervention that helps older adults better remember their personal past.

Abstract

The act of remembering an everyday experience influences how we interpret the world, how we think about the future, and how we perceive ourselves. It also enhances long-term retention of the recalled content, increasing the likelihood that it will be recalled again. Unfortunately, the ability to recollect event-specific details and reexperience the past tends to decline with age. This decline in recollection may reflect a corresponding decrease in the distinctiveness of hippocampal memory representations. Despite these well-established changes, there are few effective cognitive behavioral interventions that target real-world episodic memory. We addressed this gap by developing a smartphone-based application called HippoCamera that allows participants to record labeled videos of everyday events and subsequently replay, high-fidelity autobiographical memory cues. In two experiments, we found that older adults were able to easily integrate this noninvasive intervention into their daily lives. Using HippoCamera to repeatedly reactivate memories for real-world events improved episodic recollection and it evoked more positive autobiographical sentiment at the time of retrieval. In both experiments, these benefits were observed shortly after the intervention and again after a 3-mo delay. Moreover, more detailed recollection was associated with more differentiated memory signals in the hippocampus. Thus, using this smartphone application to systematically reactivate memories for recent real-world experiences can help to maintain a bridge between the present and past in older adults.

Neurocomputational evidence that conflicting prosocial motives guide distributive justice

A fascinating perspective and analysis from Hu et al. who show that three prosocial motives (fairness, harm aversion, and rank reversal aversion) are encoded by separate neural systems, compete for representation in various brain areas processing equality and harm signals, and are integrated in the striatum, which functions as a crucial hub for translating the motives to behavior (see also the commentary by Armstrong and McKee).  

Significance

Resource allocation in human societies usually triggers discussions about fairness, but satisfactory solutions to distribution problems also involve other prosocial motives that may prescribe different actions. Here, we address how the human brain mitigates such conflicts between multiple prosocial motives (fairness, harm aversion, and rank reversal aversion) during wealth distribution. Combining a experimental paradigm with fMRI and integrated neurocomputational modeling, we show that different prosocial motives are separately represented and integrated into choices by neural activity in striatum and its interactions with different brain regions. These findings extend unidimensional economic theories of third-party social preferences, characterize biological bases for individual and contextual differences in resource distribution behavior, and have economic and political implications for the design of taxation policies.

Abstract

In the history of humanity, most conflicts within and between societies have originated from perceived inequality in resource distribution. How humans achieve and maintain distributive justice has therefore been an intensely studied issue. However, most research on the corresponding psychological processes has focused on inequality aversion and has been largely agnostic of other motives that may either align or oppose this behavioral tendency. Here we provide behavioral, computational, and neuroimaging evidence that distribution decisions are guided by three distinct motives—inequality aversion, harm aversion, and rank reversal aversion—that interact with each other and can also deter individuals from pursuing equality. At the neural level, we show that these three motives are encoded by separate neural systems, compete for representation in various brain areas processing equality and harm signals, and are integrated in the striatum, which functions as a crucial hub for translating the motives to behavior. Our findings provide a comprehensive framework for understanding the cognitive and biological processes by which multiple prosocial motives are coordinated in the brain to guide redistribution behaviors. This framework enhances our understanding of the brain mechanisms underlying equality-related behavior, suggests possible neural origins of individual differences in social preferences, and provides a new pathway to understand the cognitive and neural basis of clinical disorders with impaired social functions.

Can we move beyond social media's current destruction of civil society?

I strongly recommend that you read Ezra Klein's NYTimes essay on Twitter. He begins by noting that the metaphor of Twitter as a global town square is wrong on three levels. I pass on some clips:

First, there isn’t, can’t be and shouldn’t be a “global town square.” The world needs many town squares, not one. Public spaces are rooted in the communities and contexts in which they exist. This is true, too, for Twitter, which is less a singular entity than a digital multiverse. What Twitter is for activists in Zimbabwe is not what it is for gamers in Britain.

Second, town squares are public spaces, governed in some way by the public. That is what makes them a town square rather than a square in a town. They are not the playthings of whimsical billionaires. They do not exist, as Twitter did for so long, to provide returns to shareholders...A town square controlled by one man isn’t a town square. It’s a storefront, an art project or possibly a game preserve.

Third, what matters for a polity isn’t the mere existence of a town square but the condition the townspeople are in when they arrive. Town squares can host debates. They can host craft fairs. They can host brawls. They can host lynchings. Civilization does not depend on a place to gather. It depends on what happens when people gather.

Twitter has real strengths, many of which are the flip side of its weaknesses. It is as flat a medium as any that has existed. It is as fast a medium as has ever existed; that can be maddening, but it can also draw attention to something that is happening and has to change right now. It is an unusually confrontational medium, and that has permitted movements like Black Lives Matter and #MeToo to flower and for socialists to get a new hearing in American politics — and it has also, of course, given new succor and life to the racist right. Put simply, Twitter’s value is how easy it makes it to talk. Its cost is how hard it makes it to listen.

It is a failure of imagination to think that our choice is the social media platforms we have now or nothing. I keep thinking about something that Robin Sloan, a novelist and former Twitter employee, wrote this year: “There are so many ways people might relate to one another online, so many ways exchange and conviviality might be organized. Look at these screens, this wash of pixels, the liquid potential! What a colossal bummer that Twitter eked out a local maximum, that its network effect still (!) consumes the fuel for other possibilities, other explorations.”

What’s surprised me most as Twitter has convulsed in recent weeks is how threadbare the social media cupboard really is. So many are open to trying something new, but as of yet, there’s nothing that feels all that new to try. Everything feels like a take on Twitter. It may be faster or slower, more decentralized or more moderated, but they’re all variations on the same theme: experiments in how to capture attention rather than deepen it, platforms built to encourage us to speak rather than to help us listen or think.

We do not make our best decisions, as individuals or as a collective, when our minds are most active and fretful. And yet “active and fretful” is about as precise a description as I can imagine of the Twitter mind. And having put us in an active, fretful mental state, Twitter then encourages us to fire off declarative statements on the most divisive possible issues, always with one eye to how quickly they will rack up likes and retweets and thus viral power. It’s insane.

And it will get so much worse from here. OpenAI recently released ChatGPT, an artificial intelligence system that can be given requests in plain language and spit out remarkably passable results...What ChatGPT can do is a marvel. We are at the dawn of a new technological era. But it is easy to see how it could turn dark — and quickly. A.I. systems like this make the production and manipulation of text (and code and images and eventually audio and video) functionally costless. They will be deployed to produce whatever makes us most likely to click. But these systems do not and cannot know what they are producing. The cost of creating and optimizing content that grabs our attention is plummeting, but the cost of producing valuable and truthful work isn’t.

These are technologies that lend themselves to cacophony, not community. I fear a world in which the business models behind them run on our attention or profit off our anger. But other worlds and other models are possible.

In Taiwan, as described by Audrey Tang, Taiwan’s minister of digital affairs, key parts of digital infrastructure are managed at the level of what we sometimes call civil society — the layer of associations and organizations between the government and the market.. The PTT Bulletin Board System is still owned by the student group that started it. It was part of how Taiwan responded so early and so effectively to the coronavirus. “It has no shareholders,” Tang said. “No advertisers. It is entirely within the academic network. It’s entirely open source. It's entirely community governed. People can freely join it. It’s a public digital space.”

Wikipedia remains one of the most-visited sites on the web, and it is owned and managed by the nonprofit Wikimedia Foundation. It shows. Wikipedia has never tried to become more than it is. It never pivoted to video or remade itself around an algorithmic feed in order to harvest more of our attention. It is a commons but one that is governed so we may use it rather than so that it may use us. It gives so much more than it takes. It thrives, quietly and gently, as a reminder that a very different internet, governed in a very different way, intended for a very different purpose, is possible.

There are those who believe the social web is reaching its terminal point. I hope they’re right. Platform after platform was designed to make it easier and more addictive for us to share content with one another so the corporations behind them could sell ever more of our attention and data. In different ways, most of these platforms are now in decline.

What if the next turn of the media dial was measured not by how much attention we gave to a platform but by how much it gave to us? I am not sure what such a service would look like. But I am hungry for it, and I suspect a lot of other people are, too.

The dawn of mediocre computing.

This post is a followup on MindBlog's 12/07/22 post on OpenAI's ChatGPT essay generating system. It was mentioned in Venkatesh Rao's essay "The Dawn of Mediocre Computing" that my techie son, Jonathan Bownds,sent to me. After pasting in the first two paragraphs of Rao's article, I want to pass on some essential clips that Jon extracted from Rao's overly long text, the sort of logorrheic writing that is responsible for the TLDR (too long didn't read) acronym. 

Well, we all knew it was coming. Computers already easily overwhelm the best humans at chess and Go. Now they have done something far harder: achieved parity with David Brooks at writing.

OpenAI’s ChatGPT, released as a research beta two days ago, has done to the standard high-school essay what cameras did to photorealistic painting and pocket calculators did to basic arithmetic. It is open sign-up and free for now, but I suspect not for much longer, so go try it; and make sure to trawl social media for interesting and revealing examples being posted by people.

Definitions:

Mediocre computing is computing that aims for parity with mediocre human performance in a realish domains where notions of excellence are ill-posed.

Excellent computing is computing that aims to surpass the best-performing humans in stylized, closed-world domains where notions of excellence are well-posed.

Most of us spend most of our time in realish domains. The urban built environment, workplaces, shopping, and modern systems of roads are all examples of realish domains. But I want to focus on two big and important ones in particular: language and money. Vast numbers of mediocre humans make good livings producing words and/or moving money around. These activities are also the home domains of the two frontiers of computing today, Al and crypto. The Second and First Foundations of the mediocre future of computing.

Via seemingly unrelated computational pathways, these two realish domains have succumbed to computerized automation. Incompletely, imperfectly, and unreliably, to be sure, but they definitely have succumbed. And in ways that seem conceptually roughly right rather than not even wrong. Large language models (LLMs) are the right way for software to eat language. Blockchains are the right way for software to eat money. And the two together are the right way to eat everything from contracts to code.

This reeks of real yin-yangery that extends to the roots of computing somehow. It's not just me hallucinating patterns where there are none.

I'm not trying to be cute here. I sincerely believe mediocre computing in realish domains is not just harder than excellent computing in stylized domains, but constitutes a whole higher category of hardness. There is an element of Moravec's paradox in my reasoning here. Roughly, the paradox states that tasks that look simple, and which all humans can do, are harder for Als than tasks that look hard, and which seem like exceptional achievements among humans.

Individuals prefer to harm their own group rather than help an opposing group

From Gershon and Fridman:  

Significance

Understanding the principles guiding decisions in intergroup conflicts is essential to recognizing the psychological barriers to compromise and cooperation. We introduce a novel paradigm for studying group decision-making, demonstrating that individuals are so averse to supporting opposing groups that they prefer equivalent or greater harm to their own group instead. While previous models of group decision-making claim that group members are driven by a desire to benefit their in-group (“in-group love”) rather than harm their out-group, our results cannot be explained by in-group love or by a harm minimizing strategy. Instead, we propose that identity concerns drive this behavior. Our theorizing speaks to research in psychology, political theory, and negotiations by examining how group members navigate trade-offs among competing priorities.

Abstract

Group-based conflict enacts a severe toll on society, yet the psychological factors governing behavior in group conflicts remain unclear. Past work finds that group members seek to maximize relative differences between their in-group and out-group (“in-group favoritism”) and are driven by a desire to benefit in-groups rather than harm out-groups (the “in-group love” hypothesis). This prior research studies how decision-makers approach trade-offs between two net-positive outcomes for their in-group. However, in the real world, group members often face trade-offs between net-negative options, entailing either losses to their group or gains for the opposition. Anecdotally, under such conditions, individuals may avoid supporting their opponents even if this harms their own group, seemingly inconsistent with “in-group love” or a harm minimizing strategy. Yet, to the best of our knowledge, these circumstances have not been investigated. In six pre-registered studies, we find consistent evidence that individuals prefer to harm their own group rather than provide even minimal support to an opposing group across polarized issues (abortion access, political party, gun rights). Strikingly, in an incentive-compatible experiment, individuals preferred to subtract more than three times as much from their own group rather than support an opposing group, despite believing that their in-group is more effective with funds. We find that identity concerns drive preferences in group decision-making, and individuals believe that supporting an opposing group is less value-compatible than harming their own group. Our results hold valuable insights for the psychology of decision-making in intergroup conflict as well as potential interventions for conflict resolution.

Autism attenuates the perception of the mind-body divide

A fascinating piece of work from Berent et al.:  

Significance

Across cultures, people consider the mind as ethereal, distinct from the body. But whether Dualism arises only from culture (nurture) or also spontaneously (from human nature) is unknown. To address this question, here, we turn to autism spectrum disorder (ASD)—a congenital disorder that compromises intuitive reasoning about the minds of others (theory of mind, ToM). If ToM promotes Dualist reasoning, then Dualist reasoning ought to be attenuated in ASD. Our results show that, compared to controls, people with ASD are more likely to view bodies and minds alike (in line with Physicalism). Moreover, a Physicalist stance is linked to difficulties with ToM. These results shed light on ASD and on the mind-body distinction in humans.

Abstract

People are intuitive Dualists—they tacitly consider the mind as ethereal, distinct from the body. Here we ask whether Dualism emerges naturally from the conflicting core principles that guide reasoning about objects, on the one hand, and about the minds of agents (theory of mind, ToM), on the other. To address this question, we explore Dualist reasoning in autism spectrum disorder (ASD)—a congenital disorder known to compromise ToM. If Dualism arises from ToM, then ASD ought to attenuate Dualism and promote Physicalism. In line with this prediction, Experiment 1 shows that, compared to controls, people with ASD are more likely to view psychological traits as embodied—as likely to manifest in a replica of one’s body. Experiment 2 demonstrates that, unlike controls, people with ASD do not consider thoughts as disembodied—as persistent in the afterlife (upon the body’s demise). If ASD promotes the perception of the psyche as embodied, and if (per Essentialism) embodiment suggests innateness, then ASD should further promote Nativism—this bias is shown in Experiment 3. Finally, Experiment 4 demonstrates that, in neurotypical (NT) participants, difficulties with ToM correlate with Physicalism. These results are the first to show that ASD attenuates Dualist reasoning and to link Dualism to ToM. These conclusions suggest that the mind-body distinction might be natural for people to entertain.

How modern human brains are different from those of other hominids and chimps.

Work pointed to in the previous post continues to add to the list of behaviors once presumed to be unique to humans that have now been found in other animals (morality, having a ‘self’, etc.) Previous MindBlog posts (list, von Economo neurons etc. do search..) have noted emerging evidence for brain features unique to - or much more pronounced in - humans than other primates. Now Pinson et al. have found that a single amino acid change in the transketolase-like 1 (TKTL1) protein on production of basal radial glia, the workhorses that generate much of the neocortex, appears that the modern human has more neocortex to work with than the ancient Neanderthal did. Here is their abstract:

Neanderthal brains were similar in size to those of modern humans. We sought to investigate potential differences in neurogenesis during neocortex development. Modern human transketolase-like 1 (TKTL1) differs from Neanderthal TKTL1 by a lysine-to-arginine amino acid substitution. Using overexpression in developing mouse and ferret neocortex, knockout in fetal human neocortical tissue, and genome-edited cerebral organoids, we found that the modern human variant, hTKTL1, but not the Neanderthal variant, increases the abundance of basal radial glia (bRG) but not that of intermediate progenitors (bIPs). bRG generate more neocortical neurons than bIPs. The hTKTL1 effect requires the pentose phosphate pathway and fatty acid synthesis. Inhibition of these metabolic pathways reduces bRG abundance in fetal human neocortical tissue. Our data suggest that neocortical neurogenesis in modern humans differs from that in Neanderthals.

OpenAI’s ChatGPT answers some questions from MindBlog

Given a recent posting in which I played with the DALL-E 2 A.I. system that generates images when you tell it what you want to see, I was motivated by a Venkatesh Rao essay "The Dawn of Mediocre Computing" to try out an essay generating system - OpenAI's ChatGPT, released as a research beta several days ago. After puttering through a number of references and joining the OpenAI Discord Server, I fundamentally don't get it and have nothing original to pass on in this post, but I thought some MindBlog readers might enjoy spending some time in the rabbit hole I am just now exiting. I pass on the following MindBlog queries and ChatGPT's rather remarkable replies: 

Question: what is the predictive processing model for brain function? 

The predictive processing model is a framework for understanding how the brain works. It proposes that the brain is constantly generating predictions about the world around us and that these predictions are used to inform our perception, behavior, and action. According to this model, the brain is always trying to make sense of the sensory information it receives by comparing it to its internal models and predictions. If there is a mismatch between the sensory information and the brain's predictions, this can lead to the experience of surprise or prediction error. The brain then uses this prediction error to update its internal models and make more accurate predictions in the future. This process is thought to be the basis for how we learn and adapt to our environment. 

Question: What are the main models for brain function? 

There are many different models or frameworks for understanding how the brain works, each of which offers a different perspective on brain function. Some of the most prominent and well-known models include the following:

The neural network model, which proposes that the brain is composed of interconnected networks of neurons that communicate with each other through electrical and chemical signals.

The cognitive model, which emphasizes the role of higher-level cognitive processes such as attention, memory, and decision-making in brain function.

The computational model, which views the brain as a biological computer that processes information using algorithms and rules.

The systems model, which focuses on the ways in which different brain regions and systems interact to produce complex behaviors and mental states.

The evolutionary model, which emphasizes the role of natural selection in shaping the brain and its functions.

The dynamic systems model, which proposes that the brain is a complex, self-organizing system that is constantly adapting and changing in response to experience. 

Each of these models offers a different perspective on brain function and can be used to help understand different aspects of the brain and its behavior.

Question: Explain critical race theory 

Critical race theory is a school of thought that explores the ways in which race and racism affect and are embedded in the laws, policies, and social structures of society. It is a framework for understanding how society and its institutions can perpetuate inequality along racial lines, and it emphasizes the importance of examining the interplay between race, power, and the law. Critical race theory is often used as a lens for analyzing issues related to inequality and social justice. It is a critical approach to the study of race and racism that seeks to challenge and dismantle the ways in which race and racism operate in society. 

ADDENDUM: I suggest readers have a look at this article on "Sentience and Sensibility"

A collection of animal stories

I've accumulated several items on animal behaviors in my list of potential post subjects, and have decided to simply pass them on to allow animal curious MindBlog readers to have a look. 

Farad Manjoo notes that ants, not humans, own the world. 

Not only land animals like humans toss objects at irritating neighbors, octopuses who gather at feeding sites with abundant food and competition for it sometimes throw silt at each other.

Crows understand the concept of recursion as well as children, and better than macaque monkeys. 

Wild Chimpanzees display declarative referential gesturing.

 

 

 

 

 

 

 

The Z-Library Kerfuffle and the whack-a-mole problem

Several months ago a friend told me about the Z-Library that he was using to download recently published fiction to evaluate candidates for book club reading. He thought it was sanctioned by publishers. I checked it out, decided to download a book, the book looked promising, so I bought the Amazon Kindle version. As this New York Daily News article makes clear in its description of the seizing of many Z-Library domains by the FBI, it is a pirate site, a file sharing service that evades copyright restrictions. I asked Wikipedia about Z-Library, and brought up a page with a description not only of Z-Library and its recent shut down in the U.S., but learned about the existence of many shadow libraries scattered over many different countries accessed by several metasearch engines. A box on this page, partly shown in the screen clip below, indicates it is part of a series on file sharing. I went to Anna's Archive, one of sites mentioned under the heading of Academic file sharing, and was able to easily download the entire text of a copyrighted Amazon Kindle Book I had purchased. Given the thousands of motivated individuals around the world who can't afford or don't have access to publications they need or want, there seems little prospect of denting the anarchy that prevails. 

Intuitive physics learning in a deep-learning A.I. model

A fascinating open source article from Piloto et al. in Nature Human Behaviour that addresses a major shortcoming of current artifician intelligence systems:

‘Intuitive physics’ enables our pragmatic engagement with the physical world and forms a key component of ‘common sense’ aspects of thought. Current artificial intelligence systems pale in their understanding of intuitive physics, in comparison to even very young children. Here we address this gap between humans and machines by drawing on the field of developmental psychology. First, we introduce and open-source a machine-learning dataset designed to evaluate conceptual understanding of intuitive physics, adopting the violation-of-expectation (VoE) paradigm from developmental psychology. Second, we build a deep-learning system that learns intuitive physics directly from visual data, inspired by studies of visual cognition in children. We demonstrate that our model can learn a diverse set of physical concepts, which depends critically on object-level representations, consistent with findings from developmental psychology. We consider the implications of these results both for AI and for research on human cognition.

The Computational Society

The most recent issue of Trends in Cognitive Sciences presents a forum in its 25th Anniversary Series: Looking Forward. Several of the contribution are open source (you can email me to request access to those that are not), and I would like to point to Nick Charter's brief article "The computational society," passing on his initial and final comments. I suggest you read through his descriptions of what he thinks are four promising lines of work.

How do individual human minds create languages, legal systems, scientific theories, and technologies? From a cognitive science viewpoint, such collective phenomena may be considered a type of distributed computation in which human minds together solve computational problems beyond any individual. This viewpoint may also shift our perspective on individual minds.

To make the computational society more than a metaphor, we need conceptual tools and methods to understand social phenomena in information-processing terms. Fortunately, several different, yet complementary, approaches have emerged in recent years. Here I highlight four promising lines of work: (i) social interaction as computation, (ii) the computational Leviathan, (iii) collective self-correction and rationality, and (iv) computation through spontaneous order.

Cognitive science may stand on the brink of a new revolution, seeing social, organizational, and cultural processes as distributed computation. If so, we will need to look afresh at the computational role of individual minds. For example, rather than seeing each developing child as a lone minilinguist or a scientist-in-the-crib, we may, following Adam Ferguson, see humans as primarily learning to contribute to collective computations beyond the understanding of individual understanding.

The non-duality industry as a panacea for the anxieties of our times?

One of MindBlog's subject threads is meditation, and some recent posts have dealt with characterizing non-dual awareness (to find these, look in the right column of this blog, under "Selected Blog Categories, and click on 'meditation.') One of the descriptions I have pointed to is given by James Low, who has training in several lineages of Tibetan Buddhism, and has been teaching the principles of Dzogchen in Europe for over 20 years. Low's website links to an array of audio and video (YouTube and Vimeo) presentations he has done. One of the participants in a recent discussion at my house urged me to check out YouTube snippets recorded by Rupert Spiro, also British, whose YouTube videos and personal wesite (The Essence of Non-Duality) offer his teachings. 

After finding the YouTube outlets for these two meditation gurus, I googled 'non duality websites' and was rewarded with an array of rabbit holes to jump into...further teachers, and a "Nonduality Institute" that engages scientific studies of non-dual awareness. 

Perhaps an increasing number of people who engage techniques for facilitating non-dual awareness find themselves seeing and experiencing the "I" or self that feels threatened by our anxious times from a more useful perspective - an inclusive expanded awareness that includes the reporting "I" or self as just one of its many contents that include passing thoughts, perceptions, actions, and feelings.  A calm can be found in this expanded awareness that permits a  dis-association of the experienced breathing visceral center of gravity of our animal body from the emotional and linguistic veneer of politics and conflict. This does not remove the necessity of facing various societal dysfunctions, but offers the prospect of doing so without debilitating the organic physiological core from which everything we experience rises. 

The Huberman Lab Cornucopia

A friend mentioned enjoying a podcast on meditation from hubermanlab.com, so I listened to it, and decided to look a bit further into who Andrew Huberman is and what he does. Regarding his "How and Why to Meditate" podcast, I think his pedagogy is good. He does some very effective chunking of just a few core ideas and repeats them over and over again. Starting about a year ago he began to generate - completely separate from his lab research as an associate professor in the Standford University Medical School Neurobiology department - podcasts, interviews, and writing (see The Neural Network Newsletter). at an amazing rate, a veritable orgy of self-optimization nuggets ideally suited for his age cohort of 40- to 50-somethings. He has a rapid, logorrheic and rambling speaking style that, at least to me, detracts from the effectiveness of his presentations. I think MindBlog readers might enjoy clicking some of the above links and grazing through his material. Before his social media with thousands of followers persona burst on the scene, his publication list shows him puttering along the conventional academic research route, with his laboratory generating 1-4 papers a year on brain plasticity and repair, split roughly equally between laboratory research and commentary/review articles.

MindBlog in Crypto-Land Part II - Is the crypto industry headed for oblivion?

In late spring of this year, I was seduced by my son's having made a six hundred-fold return on an investment by virtue of being one of the first cohort to stick little black boxs (Helium miners costing ~$1,000) on their window sills earning HNT (Helium blockchain tokens) for transmitting and receiving signals in an 'Internet of Things" that piggybacks on existing wireless systems of cell towers and cable providers. I decided to take a sip of the koolaid and set up two Helium miners which to date have earned ~ $10 for a 0.01 % return on investment! Fortunately I decided not actually own a significant amount of any of the cryptocurrencies such as BitCoin or Etherium, and didn't face financial damage of the sort mentioned below.  I persist in liking the idea that block chain ledgers and their associated cryptocurrencies offer the promise of being a monetary system that doesn't require trust in financial institutions that are potentially intrusive or corruptible.

Krugman does not agree, and has issued his latest screed against the whole crypto context in a NYTimes Op-Ed occasioned by the recent implosion of Sam Bankman-Fried and his cryptocurrency exchange FTX:

Crypto reached its peak of public prominence last year, when Matt Damon’s “Fortune favors the brave” commercial — sponsored by the Singapore-based exchange Crypto.com — first aired...people who bought after watching the Damon ad have lost more than 70 percent of their investment.,,falling prices needn’t mean that cryptocurrencies are doomed...More telling than prices has been the collapse of crypto institutions...Most recently, FTX, one of the biggest crypto exchanges, filed for bankruptcy — and it appears that the people running it simply made off with billions of depositors’ dollars, probably using the funds in a failed effort to prop up Alameda Research, its sister firm.

After 14 years, however, cryptocurrencies have made almost no inroads into the traditional role of money. They’re too awkward to use for ordinary transactions...[they] are largely purchased through exchanges like Coinbase and, yes, FTX, which take your money and hold crypto tokens in your name...These exchanges are — wait for it — financial institutions, whose ability to attract investors depends on — wait for it again — those investors’ trust. In other words, the crypto ecosystem has basically evolved into exactly what it was supposed to replace: a system of financial intermediaries whose ability to operate depends on their perceived trustworthiness.

But if the government finally moves in to regulate crypto firms, which would, among other things, prevent them from promising impossible-to-deliver returns, it’s hard to see what advantage these firms would have over ordinary banks. Even if the value of Bitcoin doesn’t go to zero (which it still might), there’s a strong case that the crypto industry, which loomed so large just a few months ago, is headed for oblivion.

How focusing on individual-level solutions has led behavioral public policy astray

MindBlog has been staying out of politics lately, but I think it worthwhile to pass on the abstract of a forthcoming article in Behavioral and Brain Science by Chater and Loewenstein, who argue that focusing on individual rather than systemic causes of social problems has yielded disappointing results, and promotes the interests of corporate opponents of systemic change. (Motivated readers can obtain the full text by emailing me.)

An influential line of thinking in behavioral science, to which the two authors have long subscribed, is that many of society’s most pressing problems can be addressed cheaply and effectively at the level of the individual, without modifying the system in which the individual operates. We now believe this was a mistake, along with, we suspect, many colleagues in both the academic and policy communities. Results from such interventions have been disappointingly modest. But more importantly, they have guided many (though by no means all) behavioral scientists to frame policy problems in individual, not systemic, terms: to adopt what we call the “i-frame,” rather than the “s-frame.” The difference may be more consequential than i-frame advocates have realized, by deflecting attention and support away from s-frame policies. Indeed, highlighting the i-frame is a long-established objective of corporate opponents of concerted systemic action such as regulation and taxation. We illustrate our argument briefly for six policy problems, and in depth with the examples of climate change, obesity, retirement savings, and pollution from plastic waste. We argue that the most important way in which behavioral scientists can contributed to public policy is by employing their skills to develop and implement value- creating system-level change.

The neurophysiology of consciousness - neural correlates of qualia

This is a post for consciousness mavens.Tucker, Luu, and Johnson have offered a neurophyiological model of consciousness, Neurophysiological mechanisms of implicit and explicit memory in the process of consciousness. The open source article has useful summary graphics, and embraces the 'Hard Problem' of consciousness - the nature of 'qualia' (how it feels to see red, eat an apple, etc.) Here I pass on brief, and then more lengthy, paragraphs on what the authors think is new and noteworthy about their ideas.

The process of consciousness, generating the qualia that may appear to be irreducible qualities of experience, can be understood to arise from neurophysiological mechanisms of memory. Implicit memory, organized by the lemnothalamic brain stem projections and dorsal limbic consolidation in REM sleep, supports the unconscious field and the quasi-conscious fringe of current awareness. Explicit memory, organized by the collothalamic midbrain projections and ventral limbic consolidation of NREM sleep, supports the focal objects of consciousness.

Neurophysiological mechanisms are increasingly understood to constitute the foundations of human conscious experience. These include the capacity for ongoing memory, achieved through a hierarchy of reentrant cross-laminar connections across limbic, heteromodal, unimodal, and primary cortices. The neurophysiological mechanisms of consciousness also include the capacity for volitional direction of attention to the ongoing cognitive process, through a reentrant fronto-thalamo-cortical network regulation of the inhibitory thalamic reticular nucleus. More elusive is the way that discrete objects of subjective experience, such as the color of deep blue or the sound of middle C, could be generated by neural mechanisms. Explaining such ineffable qualities of subjective experience is what Chalmers has called “the hard problem of consciousness,” which has divided modern neuroscientists and philosophers alike. We propose that insight into the appearance of the hard problem can be gained through integrating classical phenomenological studies of experience with recent progress in the differential neurophysiology of consolidating explicit versus implicit memory. Although the achievement of consciousness, once it is reflected upon, becomes explicit, the underlying process of generating consciousness, through neurophysiological mechanisms, is largely implicit. Studying the neurophysiological mechanisms of adaptive implicit memory, including brain stem, limbic, and thalamic regulation of neocortical representations, may lead to a more extended phenomenological understanding of both the neurophysiological process and the subjective experience of consciousness.