Tuesday, December 18, 2018

Can we really inherit trauma?

MindBlog has mentioned a number of studies that claim that the effects of trauma can be passed through generations. Carey does a review that notes that human studies are much less persuasive than animal research using mice.
The debate centers on genetics and biology. Direct effects are one thing: when a pregnant woman drinks heavily, it can cause fetal alcohol syndrome. This happens because stress on a pregnant mother’s body is shared to some extent with the fetus, in this case interfering directly with the normal developmental program in utero.
But no one can explain exactly how, say, changes in brain cells caused by abuse could be communicated to fully formed sperm or egg cells before conception. And that’s just the first challenge. After conception, when sperm meets egg, a natural process of cleansing, or “rebooting,” occurs, stripping away most chemical marks on the genes. Finally, as the fertilized egg grows and develops, a symphony of genetic reshuffling occurs, as cells specialize into brain cells, skin cells, and the rest. How does a signature of trauma survive all of that?
...for now, and for many scientists, the research in epigenetics falls well short of demonstrating that past human cruelties affect our physiology today, in any predictable or consistent way.

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